Markitziu A
Department of Oral Medicine, Oral Diagnosis and Oral Radiology, Hebrew University-Hadassah Faculty of Dental Medicine, Jerusalem, Israel.
J Dent. 1991 Oct;19(5):304-6. doi: 10.1016/0300-5712(91)90079-e.
The solubility of molar enamel was tested in irradiated rats treated with fluoride (F-). Seventy-five 21-day-old rats were divided into five groups. The first group received F- in the drinking water (25 p.p.m.), one group was irradiated only (one single dose of 15 Gy to the head); one group was started on F- 3 weeks before irradiation, in one group the commencement of the F- regimen coincided with irradiation. The last group served as a control. The animals were sacrificed at 80 days old. Enamel solubility of the molar teeth, measured as Ca++ release in an etchant, was determined separately in three consecutive immersions. Fluoridation and irradiation reduced enamel solubility, albeit in a dissimilar depth-related amplitude. Whether administered prior to or following irradiation, F- reduced enamel solubility in a pattern resembling that of the non-irradiated F- treated group.
对用氟化物（F-）处理的辐照大鼠的磨牙牙釉质溶解度进行了测试。75只21日龄的大鼠被分为五组。第一组在饮用水中摄入F-（25 ppm），一组仅接受辐照（单次头部照射15 Gy）；一组在辐照前3周开始摄入F-，一组F-方案的开始与辐照同时进行。最后一组作为对照。动物在80日龄时处死。通过在蚀刻剂中测量Ca++释放来测定磨牙牙釉质的溶解度，在连续三次浸泡中分别进行测定。氟化和辐照降低了牙釉质溶解度，尽管在与深度相关的幅度上有所不同。无论在辐照之前还是之后给予F-，其降低牙釉质溶解度的模式都类似于未辐照的F-处理组。
