Soyman M, Stack M V
Proc Finn Dent Soc. 1989;85(3):167-75.
Various studies have shown that the solubility of dental enamel can be reduced by exposing it to metal ions in the presence of fluoride. The purpose of this study was to determine the effects of various trace metal ions at two concentrations on dental enamel solubility and fluoride uptake. The solubilities of the enamel surfaces and their fluoride concentrations were first determined. Atypical teeth were discarded. Blocks of enamel were then divided into groups of five and solutions of salts of aluminium, strontium, titanium, molybdenum and vanadium followed by fluoride (4,000 ppm) were applied. Two successive layers were then etched off, using perchloric acid. Fluoride in the enamel was determined using an ion-specific electrode system. Calcium was determined by atomic absorption spectrophotometry. The values obtained were used to calculate the thicknesses of the layers removed. The results showed that combined application of aluminium and fluoride led to a marked reduction in solubility of enamel (p less than 0.001). Application of strontium (0.01 M) and fluoride also led to a significant reduction in enamel solubility (p less than 0.01). Pretreatment with titanium solution (both concentrations), aluminium or molybdenum solutions (higher concentrations) increased fluoride uptake in comparison with the control group. Statistically significant increase in fluoride uptake was seen only in those enamels treated with titanium solution at higher concentration when compared with those treated with fluoride alone.
多项研究表明，在氟化物存在的情况下，将牙釉质暴露于金属离子中可降低其溶解度。本研究的目的是确定两种浓度的各种微量金属离子对牙釉质溶解度和氟摄取的影响。首先测定牙釉质表面的溶解度及其氟浓度。剔除不典型的牙齿。然后将牙釉质块分成每组五块，并施加铝、锶、钛、钼和钒的盐溶液，随后施加氟化物（4000 ppm）。然后使用高氯酸蚀刻掉两层连续的牙釉质。使用离子特异性电极系统测定牙釉质中的氟化物。通过原子吸收分光光度法测定钙。所得值用于计算去除层的厚度。结果表明，铝和氟化物的联合应用导致牙釉质溶解度显著降低（p小于0.001）。施加锶（0.01 M）和氟化物也导致牙釉质溶解度显著降低（p小于0.01）。与对照组相比，用钛溶液（两种浓度）、铝或钼溶液（较高浓度）预处理可增加氟摄取。与仅用氟化物处理的牙釉质相比，仅在较高浓度的钛溶液处理的牙釉质中观察到氟摄取有统计学显著增加。
