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同时或分别摄入食物和含氟饮用水的大鼠磨牙表面的牙齿磨损、溶解性和氟浓度

Tooth wear, solubility and fluoride concentration of molar-tooth surfaces in rats maintained on simultaneous or separate intake of food and fluoridated drinking water.

作者信息

Markitziu A, Salomon I, Gedalia I

出版信息

Arch Oral Biol. 1985;30(2):167-9. doi: 10.1016/0003-9969(85)90110-4.

DOI:10.1016/0003-9969(85)90110-4
PMID:3857034
Abstract

Eighty rats, 20 days old, were fed a hard pellet diet and deionized or fluoridated (25 parts/10(6) F-) drinking water respectively for 40 days. Half were maintained on simultaneous food and water intake for 3 h, daily, and the remainder on separate intake of food for 3 h followed by drinking water for 3 h, daily. Scanning electron micrographs of the occlusal surface of right maxillary first molars were used for scoring wear. The mandibular and left maxillary molar surfaces were used for solubility and fluoride concentration determinations. Intake of food and water separately did not affect wear significantly, whereas solubility and fluoride concentration of the molar surfaces were significantly increased. Wear, solubility and fluoride of the molar surfaces respectively were highly significantly increased in the rats provided with fluoridated water. Increase in fluoride uptake is due in part at least to the increase in sites available for uptake due to tooth wear. Acid dissolution of worn tooth-surface enamel is greater than that of intact enamel.

摘要

80只20日龄的大鼠分别喂食硬颗粒饲料,并分别饮用去离子水或含氟水(25份/10⁶ F⁻)40天。一半大鼠每天同时进食和饮水3小时,其余大鼠每天先进食3小时,然后饮水3小时。用右上颌第一磨牙咬合面的扫描电子显微镜照片对磨损进行评分。下颌和左上颌磨牙表面用于溶解性和氟浓度测定。分别进食和饮水对磨损没有显著影响,而磨牙表面的溶解性和氟浓度显著增加。饮用含氟水的大鼠磨牙表面的磨损、溶解性和氟含量分别显著增加。氟摄取的增加至少部分归因于牙齿磨损导致的可摄取部位增加。磨损牙齿表面釉质的酸溶解大于完整釉质。

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