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新型阳离子聚异戊二烯衍生物被提议作为一种脂质转染剂。

New cationic polyprenyl derivative proposed as a lipofecting agent.

作者信息

Madeja Zbigniew, Rak Monika, Wybieralska Ewa, Rózański Igor, Masnyk Marek, Chmielewski Marek, Lysek Robert, Chojnacki Tadeusz, Jankowski Wiesław, Ciepichal Ewa, Swiezewska Ewa, Tekle Michael, Dallner Gustav

机构信息

Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.

出版信息

Acta Biochim Pol. 2007;54(4):873-6. Epub 2007 Dec 8.

PMID:18066397
Abstract

Cationic linear poly-cis-isoprenoid prepared from natural plant polyprenol in a mixture with dioleyl phosphatidylethanolamine was found to be an effective lipofection agent for eukaryotic cells. The transfecting activity is related to the poly-cis structure of the polyprenyl chain.

摘要

由天然植物聚戊烯醇与二油酰磷脂酰乙醇胺混合制备的阳离子线性聚顺式异戊二烯被发现是一种用于真核细胞的有效脂质转染试剂。转染活性与聚异戊二烯链的聚顺式结构有关。

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