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[1990 - 2006年上海风疹流行病学特征研究]

[Study on the epidemiological characteristics of rubella from 1990-2006 in Shanghai].

作者信息

Hu Jia-Yu, Tao Li-Na, Shen Jie, Wang Yu-Chao

机构信息

Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200236, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2007 Jul;28(7):645-8.

PMID:18069550
Abstract

OBJECTIVE

This paper analyzed the epidemiological characteristics of rubella in Shanghai from 1990 to 2006.

METHODS

Descriptive epidemiological study was applied to analyze the cases from infectious diseases reported system on rubella during 1990-2006 in Shanghai. Excel was used for data analysis.

RESULTS

The reported rubella incidence rate in Shanghai was 0.15-451.57 per 100,000 during the period from 1990 to 2006. A rubella epidemic happened in 1993, with the number of reported cases as 58,104. The year 1998 was the low year on rubella with only 19 reported cases. In the years without rubella vaccine (RV), that was, from 1990 to 1994, the annual reported incidence rate of rubella was 93 per 100,000, and there was a distinct characteristic of seasonal difference, with peak in march through June each year. Rubella cases mostly affected children aged 5-9 and adolescent of 10-14 years old. Since the wide use of RV in Shanghai since 1995, RV and measles, mumps, rubella (MMR) had been widely accepted by parents. The vaccination rate of MMR reached up to 85 percent. The incidence of rubella was descending as year went by. The annual reported cases were less than 100 since then (with exception in the year 1995). Local outbreaks were further reduced and the age group structure had also changed since the adoption of RV. Patients with RV fallen into the age group of 0-4 were increasing quickly, accounting for 21.00% percent of all the patients and the age become older. 31.62% of the patients fell into 20 years of age and above. During 1995-2006, the incidence rates of rubella in age 25-29 and 30-34 were both much higher than that in the year without vaccine.

CONCLUSION

The trend of older age among patients wilt Rubella increased the risk on fertile woman and geting congenital rebella syndrome.

摘要

目的

分析1990年至2006年上海市风疹流行病学特征。

方法

采用描述性流行病学研究方法,对上海市1990 - 2006年传染病报告系统中的风疹病例进行分析,数据分析采用Excel软件。

结果

1990年至2006年上海市风疹报告发病率为每10万人口0.15 - 451.57例。1993年发生风疹流行,报告病例数为58104例。1998年是风疹发病低谷年,仅报告19例。在未使用风疹疫苗(RV)的年份,即1990年至1994年,风疹年报告发病率为每10万人口93例,有明显的季节性差异特征,每年3至6月为发病高峰。风疹病例主要集中在5 - 9岁儿童和10 - 14岁青少年。自1995年上海市广泛使用RV以来,风疹疫苗和麻疹、腮腺炎、风疹联合疫苗(MMR)被家长广泛接受,MMR疫苗接种率达85%。风疹发病率逐年下降,此后年报告病例数少于100例(1995年除外)。自使用RV以来,局部暴发进一步减少,年龄组结构也发生了变化。风疹病例中0 - 4岁年龄组患者迅速增加,占全部患者的21.00%,发病年龄有增大趋势,20岁及以上患者占31.62%。1995 - 2006年,25 - 29岁和30 - 34岁年龄组风疹发病率均远高于未接种疫苗年份。

结论

风疹患者年龄增大趋势增加了育龄妇女感染风疹及发生先天性风疹综合征的风险。

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