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自体外周血祖细胞移植后原发性胃肠道曲霉病:侵袭性曲霉病的一种不寻常表现。

Primary gastrointestinal aspergillosis after autologous peripheral blood progenitor cell transplantation: an unusual presentation of invasive aspergillosis.

作者信息

González-Vicent M, Díaz M A, Colmenero I, Sevilla J, Madero L

机构信息

Stem Cell Transplant Unit, Niño Jesús Children's Hospital, Madrid, Spain.

出版信息

Transpl Infect Dis. 2008 Jun;10(3):193-6. doi: 10.1111/j.1399-3062.2007.00288.x. Epub 2007 Dec 7.

Abstract

Primary gastrointestinal invasive aspergillosis is an unusual presentation in patients with malignancies undergoing chemotherapy. Visceral organ involvement with Aspergillus sp. most often occurs in the setting of disseminated infection. We report a case of a patient diagnosed with Wilms' tumor who developed primary gastrointestinal aspergillosis after autologous peripheral blood progenitor cell transplantation. He had no evidence of pulmonary, sinus, or central nervous system infection. The patient died of septic shock after emergency surgery.

摘要

原发性胃肠道侵袭性曲霉病在接受化疗的恶性肿瘤患者中是一种不常见的表现。曲霉菌属累及内脏器官最常发生在播散性感染的情况下。我们报告一例诊断为肾母细胞瘤的患者,在自体外周血祖细胞移植后发生原发性胃肠道曲霉病。他没有肺部、鼻窦或中枢神经系统感染的证据。该患者在急诊手术后死于感染性休克。

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