Bíres J, Vrzgula L, Juhásová Z
Vysoká skola veterinárska, Kosice.
Vet Med (Praha). 1991 Jun;36(6):361-71.
Cu, Fe, Zn, Mo, Se, As, Cd and Pb distribution was followed in the organisms of seven lambing ewes after these animals had been on a diet with industrial contaminants generated by the copper and zinc works. The amount of ingested contaminants per lambing ewe was 31.99 g a day pursuant to the starting liveweight. Per-head daily intake of Cu, Fe, Zn, Mo, Se, As, Cd and Pb in mg: 402.02; 95.97; 6158.07; 1.436; 2.975; 15.38; 0.597; 22.14. The first ewe with symptoms of zinc intoxication died on day 42 and the last on day 58. The highest Zn concentrations were recorded in the dry matter of dead ewe liver (1167.3 +/- 314.1 mg per kg). An amount of 1048 +/- 283.7 mg Zn per kg was cumulated in the kidneys in the process of contaminant administration. High Zn contents were also observed in the uterus and spleen. The highest amounts of Cu were cumulated in liver (445.6 238.1 mg per kg). Spleen was an organ with the highest concentrations of Fe, the ovaries cumulated the highest amounts of Mo and bony tissue and ovaries the highest amounts of Se. An exposure of the organisms to As, Cd and Pb in ewes intoxicated with zinc from a source of industrial pollutants, was reflected in their high contents in the ovaries, kidneys, liver and bony tissue. These results demonstrate that in sheep the liver, kidneys, uterus, spleen and ovaries are the most suitable organs if it is to prove zinc intoxication caused by pollutants from the copper and zinc works. Liver, kidneys, ovaries, uterus, spleen, skeletal muscles and bony tissue seem to be suitable for an evaluation of Cu, Fe, Mo, Se, As, Cd and Pb distribution in the organisms of ewes which died from zinc intoxication caused by pollutants from the above-mentioned source.
在七只产羔母羊食用了由铜锌厂产生的工业污染物的饲料后,跟踪观察了它们体内铜、铁、锌、钼、硒、砷、镉和铅的分布情况。根据起始活重,每只产羔母羊每天摄入的污染物量为31.99克。每只母羊每天摄入铜、铁、锌、钼、硒、砷、镉和铅的毫克数分别为:402.02;95.97;6158.07;1.436;2.975;15.38;0.597;22.14。第一只出现锌中毒症状的母羊在第42天死亡,最后一只在第58天死亡。死亡母羊肝脏干物质中锌浓度最高(每千克1167.3±314.1毫克)。在污染物投喂过程中,肾脏中累积了每千克1048±283.7毫克的锌。子宫和脾脏中也观察到高锌含量。肝脏中累积的铜含量最高(每千克445.6±238.1毫克)。脾脏是铁浓度最高的器官,卵巢中累积的钼含量最高,骨组织和卵巢中累积的硒含量最高。来自工业污染源锌中毒的母羊体内砷、镉和铅的暴露情况,体现在卵巢、肾脏、肝脏和骨组织中的高含量上。这些结果表明,对于证明是由铜锌厂污染物导致的锌中毒而言,在绵羊中肝脏、肾脏、子宫、脾脏和卵巢是最合适的器官。肝脏、肾脏、卵巢、子宫、脾脏、骨骼肌和骨组织似乎适合用于评估因上述污染源污染物导致锌中毒死亡的母羊体内铜、铁、钼、硒、砷、镉和铅的分布情况。