Cooper G M, McClure J H
University of Birmingham and Birmingham Women's Hospital, Birmingham, UK.
Br J Anaesth. 2008 Jan;100(1):17-22. doi: 10.1093/bja/aem344.
This chapter concerning maternal mortality due to anaesthesia, reprinted with permission from Saving Mothers' Lives, is the 18th in a series of reports within the Confidential Enquiries into Maternal and Child Health (CEMACH) in the UK. In the years 2003-05 there were six women who died from problems directly related to anaesthesia, which is the same as the 2000-02 triennium. Obesity was a factor in four of these women who died. Two of these deaths were in women in early pregnancy, who received general anaesthesia for gynaecological surgery by inexperienced anaesthetists who failed to manage the airway and ventilation adequately. When trainee anaesthetists are relatively inexperienced their consultants must know the limits of their competence and when close supervision and help may be needed. One death was due to bupivacaine toxicity due to a drug administration error when a bag of dilute local anaesthetic was thought to be intravenous fluid. In a further 31 cases poor perioperative management may have contributed to death. Obesity was again a relevant factor. Other cases could be categorized into poor recognition of women being sick and poor clinical management of haemorrhage, sepsis and of pre-eclampsia. Early warning scores of vital signs may help identify the mother who is seriously ill. Learning points are highlighted in relation to the clinical management of these obstetric complications.
本章关于麻醉导致的孕产妇死亡,经《拯救母亲生命》授权重印,是英国孕产妇和儿童健康保密调查(CEMACH)系列报告中的第18份。在2003 - 2005年期间,有6名女性死于与麻醉直接相关的问题,这与2000 - 2002三年期相同。肥胖是其中4名死亡女性的一个因素。其中2例死亡发生在早孕女性身上,她们因妇科手术接受全身麻醉,麻醉师经验不足,未能充分管理气道和通气。当实习麻醉师经验相对不足时,其指导医生必须了解他们的能力极限以及何时可能需要密切监督和帮助。1例死亡是由于药物管理错误导致布比卡因中毒,当时一袋稀释的局部麻醉药被误当作静脉输液。在另外31例病例中,围手术期管理不善可能导致了死亡。肥胖再次成为一个相关因素。其他病例可归类为对患病女性识别不足以及对出血、败血症和子痫前期的临床管理不善。生命体征的早期预警评分可能有助于识别病情严重的母亲。文中突出了与这些产科并发症临床管理相关的经验教训。