Lally P, Chipperfield A, Wardle J
Department of Epidemiology and Public Health, Health Behaviour Unit, University College London, London, UK.
Int J Obes (Lond). 2008 Apr;32(4):700-7. doi: 10.1038/sj.ijo.0803771. Epub 2007 Dec 11.
To evaluate the efficacy of a simple weight loss intervention, based on principles of habit formation.
An exploratory trial in which overweight and obese adults were randomized either to a habit-based intervention condition (with two subgroups given weekly vs monthly weighing; n=33, n=36) or to a waiting-list control condition (n=35) over 8 weeks. Intervention participants were followed up for 8 months.
A total of 104 adults (35 men, 69 women) with an average BMI of 30.9 kg m(-2).
Intervention participants were given a leaflet containing advice on habit formation and simple recommendations for eating and activity behaviours promoting negative energy balance, together with a self-monitoring checklist.
Weight change over 8 weeks in the intervention condition compared with the control condition and weight loss maintenance over 32 weeks in the intervention condition.
At 8 weeks, people in the intervention condition had lost significantly more weight (mean=2.0 kg) than those in the control condition (0.4 kg), with no difference between weekly and monthly weighing subgroups. At 32 weeks, those who remained in the study had lost an average of 3.8 kg, with 54% losing 5% or more of their body weight. An intention-to-treat analysis (based on last-observation-carried-forward) reduced this to 2.6 kg, with 26% achieving a 5% weight loss.
This easily disseminable, low-cost, simple intervention produced clinically significant weight loss. In limited resource settings it has potential as a tool for obesity management.
基于习惯养成原则评估一种简单的减肥干预措施的效果。
一项探索性试验，超重和肥胖的成年人被随机分为基于习惯的干预组（两个亚组，分别为每周称重组和每月称重组；n = 33，n = 36）或等待名单对照组（n = 35），为期8周。对干预组参与者进行8个月的随访。
共104名成年人（35名男性，69名女性），平均体重指数为30.9 kg/m²。
为干预组参与者提供一份包含习惯养成建议以及促进负能量平衡的饮食和活动行为简单建议的传单，以及一份自我监测清单。
干预组与对照组在8周内的体重变化，以及干预组在32周内的体重减轻维持情况。
在8周时，干预组的体重减轻显著多于对照组（平均减轻2.0 kg）（对照组为0.4 kg），每周称重亚组和每月称重亚组之间无差异。在32周时，仍留在研究中的参与者平均体重减轻了3.8 kg，54%的人体重减轻了5%或更多。意向性分析（基于末次观察结转）将这一数字降至2.6 kg，26%的人体重减轻了5%。
这种易于传播、低成本、简单的干预措施产生了具有临床意义的体重减轻。在资源有限的环境中，它有潜力作为肥胖管理的一种工具。
