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肾发育异常与磁共振成像:临床医生视角

Renal dysplasia and MRI: a clinician's perspective.

作者信息

Greenbaum Larry A

机构信息

Division of Pediatric Nephrology, Children's Healthcare of Atlanta, Emory University, 2015 Uppergate Drive NE, Atlanta, GA 30322, USA.

出版信息

Pediatr Radiol. 2008 Jan;38 Suppl 1:S70-5. doi: 10.1007/s00247-007-0586-y. Epub 2007 Dec 11.

DOI:10.1007/s00247-007-0586-y
PMID:18071696
Abstract

Renal dysplasia is a common abnormality in children. The role of MRI in evaluating children with renal dysplasia is evolving. More information is clearly necessary before MRI replaces conventional imaging modalities. In order to appropriately use MRI, the radiologist must have an understanding of the clinical questions that are important in the management of children with renal dysplasia. This review provides background information on renal dysplasia for the pediatric radiologist. The focus is on unilateral disease, especially multicystic dysplastic kidneys, and bilateral dysplasia, which is the most common cause of kidney failure in children. The emphasis is on the important clinical issues, and the potential of MRI as a methodology for providing clinically useful information not otherwise available from other imaging modalities.

摘要

肾发育异常是儿童常见的异常情况。MRI在评估肾发育异常儿童中的作用正在不断发展。在MRI取代传统成像方式之前,显然需要更多信息。为了合理使用MRI,放射科医生必须了解在肾发育异常儿童管理中重要的临床问题。本综述为儿科放射科医生提供了有关肾发育异常的背景信息。重点是单侧疾病,尤其是多囊性发育不良肾,以及双侧发育异常,这是儿童肾衰竭最常见的原因。重点是重要的临床问题,以及MRI作为一种能够提供其他成像方式无法获得的临床有用信息的方法的潜力。

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本文引用的文献

1
Prevalence of mutations in renal developmental genes in children with renal hypodysplasia: results of the ESCAPE study.肾发育不全儿童肾发育基因的突变患病率:ESCAPE研究结果
J Am Soc Nephrol. 2006 Oct;17(10):2864-70. doi: 10.1681/ASN.2006030277. Epub 2006 Sep 13.
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Noninvasive assessment of early kidney allograft dysfunction by blood oxygen level-dependent magnetic resonance imaging.通过血氧水平依赖性功能磁共振成像对早期肾移植功能障碍进行无创评估。
Transplantation. 2006 Sep 15;82(5):621-8. doi: 10.1097/01.tp.0000234815.23630.4a.
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Single kidney and sports participation: perception versus reality.
经脐多通道腹腔镜肾盂输尿管切除术治疗儿童先天性肾发育不良:单中心中期随访结果。
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Imaging chronic renal disease and renal transplant in children.儿童慢性肾脏病和肾移植的影像学诊断
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Histomorphology of renal dysplasia--an autopsy study.肾发育异常的组织形态学——一项尸检研究
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Nephrogenic systemic fibrosis: suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging.肾源性系统性纤维化:钆双胺用于增强磁共振成像的疑似致病作用
J Am Soc Nephrol. 2006 Sep;17(9):2359-62. doi: 10.1681/ASN.2006060601. Epub 2006 Aug 2.
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Volume progression in polycystic kidney disease.多囊肾病中的体积进展
N Engl J Med. 2006 May 18;354(20):2122-30. doi: 10.1056/NEJMoa054341.
7
Risk of Wilms' tumour with multicystic kidney disease: a systematic review.多囊肾病患儿患肾母细胞瘤的风险:一项系统评价
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Obesity-associated hypertension: new insights into mechanisms.肥胖相关性高血压:机制新见解
Hypertension. 2005 Jan;45(1):9-14. doi: 10.1161/01.HYP.0000151325.83008.b4. Epub 2004 Dec 6.
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BMC Nephrol. 2004 Oct 5;5:12. doi: 10.1186/1471-2369-5-12.
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