癌症患者中，与癌症相关的疲劳与血液学因素还是心理因素的相关性更强？
Is cancer-related fatigue more strongly correlated to haematological or to psychological factors in cancer patients?
作者信息
Romito F, Montanaro R, Corvasce C, Di Bisceglie M, Mattioli V
机构信息
Experimental Unit of Psycho-Oncology, Department of Critical Area and Surgery Room, National Cancer Institute "GIOVANNI PAOLO II", Via Samuel Hanhemann 10, 70126, Bari, Italy.
出版信息
Support Care Cancer. 2008 Aug;16(8):943-6. doi: 10.1007/s00520-007-0357-1. Epub 2007 Dec 11.
GOALS OF WORK
Cancer-related fatigue is a very frequent problem in cancer, interfering with many patients' life activities. Anaemia is present in a large number of fatigued patients. The aim of this study was to evaluate cancer-related fatigue, in relation with haematic haemoglobin levels and the presence of anxiety and depression.
MATERIALS AND METHODS
The Functional Assessment Of Chronic Illness Therapy-Fatigue scale was used to assess fatigue. The Hospital Anxiety and Depression Scale was administered to screen for psychological distress. Haematological values were measured by blood tests. All data were analysed using Chi-squared, and a logistic regression analysis was conducted.
MAIN RESULTS
Eighty patients were enrolled in the study. Significant associations were found between fatigue and depression, fatigue and anxiety and between fatigue and haemoglobin.
CONCLUSION
Anxiety and depression, other than heamoglobin levels, were found associated with fatigue. Hence, implications for a multi-dimensional treatment of fatigue are discussed.
工作目标
癌症相关疲劳是癌症患者中非常常见的问题，会干扰许多患者的生活活动。大量疲劳患者存在贫血症状。本研究的目的是评估与癌症相关的疲劳，以及与血红蛋白水平、焦虑和抑郁之间的关系。
材料与方法
采用慢性病治疗功能评估-疲劳量表评估疲劳程度。使用医院焦虑抑郁量表筛查心理困扰。通过血液检测测量血液学指标。所有数据采用卡方检验进行分析，并进行逻辑回归分析。
主要结果
80名患者纳入本研究。研究发现疲劳与抑郁、疲劳与焦虑以及疲劳与血红蛋白之间存在显著关联。
结论
除血红蛋白水平外，焦虑和抑郁也与疲劳有关。因此，本文讨论了对疲劳进行多维度治疗的意义。
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