Jenkinson M D, Du Plessis D G, Walker C, Smith T S
Department of Neurosurgery, Walton Centre for Neurology and Neurosurgery, University of Liverpool, UK.
Br J Neurosurg. 2007 Dec;21(6):550-61. doi: 10.1080/02688690701642020.
Gliomas are a heterogeneous group that account for approximately 86% of primary brain neoplasms, and include astrocytic and oligodendroglial tumours, as well as a variety of less common histopathological subtypes. Magnetic resonance imaging has become the accepted mode of imaging for the clinical management of these tumours. MRI features bear close resemblance to the histopathology grading and prognosis of these tumours. Currently, conventional MRI is used to aid diagnosis, plan neurosurgical approaches, and monitor response to therapy and disease progression. More recent developments in the field of MRI include MR spectroscopy, perfusion MRI, diffusion-weighted imaging, intraoperative MRI and functional MRI. These newer techniques have been adopted with varying success in the management of adult gliomas. This review focuses on the application of advanced MR imaging in the clinical management of adult gliomas.
胶质瘤是一组异质性肿瘤，约占原发性脑肿瘤的86%，包括星形细胞瘤和少突胶质细胞瘤，以及各种不太常见的组织病理学亚型。磁共振成像已成为这些肿瘤临床管理中公认的成像方式。MRI特征与这些肿瘤的组织病理学分级和预后密切相关。目前，传统MRI用于辅助诊断、规划神经外科手术方法以及监测治疗反应和疾病进展。MRI领域的最新进展包括磁共振波谱、灌注MRI、扩散加权成像、术中MRI和功能MRI。这些新技术在成人胶质瘤的管理中应用的成功程度各不相同。本综述重点关注先进MR成像在成人胶质瘤临床管理中的应用。
