Dahlhausen Bob
Veterinary Molecular Diagnostics, Inc., Milford, OH USA.
J Exot Pet Med. 2010 Apr;19(2):117-132. doi: 10.1053/j.jepm.2010.05.006. Epub 2010 Sep 19.
The development of rapid, accurate, and sensitive diagnostic methods for detecting pathogens is the basis for treating, controlling, and eradicating infectious diseases of veterinary importance. Scientific and technological advancements have revolutionized the field of veterinary diagnostics. Genome sequencing has allowed efficient, sensitive, and specific diagnostic assays to be developed based on the detection of nucleic acids. The integration of advances in biochemistry, proteomics, engineering, and medicine offers enormous potential for the rapid and accurate diagnosis of viral, microbial, genetic, and metabolic disease. In the future, polymerase chain reaction assays, microarray testing, genomic analysis, and metabolic profiling will be accomplished in a rapid, portable, sensitive, and cost-efficient manner.
开发快速、准确且灵敏的病原体检测诊断方法是治疗、控制和根除具有兽医重要性的传染病的基础。科技进步彻底改变了兽医诊断领域。基因组测序使得基于核酸检测开发高效、灵敏且特异的诊断检测方法成为可能。生物化学、蛋白质组学、工程学和医学领域的进展相结合，为快速准确诊断病毒、微生物、遗传和代谢疾病提供了巨大潜力。未来，聚合酶链反应检测、微阵列检测、基因组分析和代谢谱分析将以快速、便携、灵敏且经济高效的方式完成。
