Martin H
Dental Department, Veterans Administration Medical Center, Washington, D.C.
Curr Opin Dent. 1991 Dec;1(6):734-6.
Disinfection is a key aspect in the preparation of root canals prior to obturation. Irrigation and intracanal medicaments are the chemical means of debridement. The bacterial role is significant, and intracanal medicaments must be cidal in their effect on bacteria and the dentinal tubules. Topical application of medicaments seem to be as effective or more effective than antibiotic applications. Glutaraldehyde and calcium hydroxide are two of the more recently studied medicaments. Calcium hydroxide shows promise as an effective microbicide. The importance of removal of bacteria and necrotic debris from the canal by chemomechanical means--mechanical preparation, cidal irrigation, antimicrobial medicaments--will enhance the successful outcome of endodontic therapy.
消毒是根管充填前根管预备的关键环节。冲洗和根管内用药是化学清创方法。细菌的作用至关重要，根管内用药必须对细菌和牙本质小管具有杀菌作用。局部用药似乎与抗生素应用效果相当或更有效。戊二醛和氢氧化钙是最近研究较多的两种药物。氢氧化钙有望成为一种有效的杀菌剂。通过化学机械方法——机械预备、杀菌冲洗、抗菌药物——从根管中清除细菌和坏死碎屑的重要性，将提高牙髓治疗的成功率。
