Bartók I, Virágh S, Menyhárt J
Acta Morphol Acad Sci Hung. 1975;23(2):145-55.
Male albino rats were deprived of water for 6 days, then they were allowed to drink tap water ad libitim. The structure of the liver was examined by light and electron microscopy, and the protein and dry matter contents, oxygen consumption and glucose-6-phosphatase activity of the liver were determined after rehydration. At 10 minutes, the mitochondria showed signs of division and a peculiar transformation of the cristae. At 60 minutes, the membranes of the rough endoplasmic reticulum were found to have proliferated. At 12 hours, the smooth-surfaced membranes showed hypertrophy and the bile canaliculi were distended. At 24 hours all rehydration induced organelle alterations were declining. The biochemical findings agreed well with the fine structural changes and both were indicative of an enchanced functional capacity of liver cells during rehydration.
将雄性白化大鼠禁水6天，然后让它们自由饮用自来水。通过光学显微镜和电子显微镜检查肝脏结构，并在复水后测定肝脏的蛋白质和干物质含量、耗氧量以及葡萄糖-6-磷酸酶活性。在10分钟时，线粒体出现分裂迹象，嵴发生特殊转变。在60分钟时，发现粗面内质网的膜已经增殖。在12小时时，光滑表面的膜出现肥大，胆小管扩张。在24小时时，所有复水诱导的细胞器改变都在消退。生化结果与精细结构变化非常吻合，两者均表明复水期间肝细胞的功能能力增强。
