Nicholas M Kelly
University of Chicago, Department of Neurology, MC 2030, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
Expert Rev Anticancer Ther. 2007 Dec;7(12 Suppl):S23-7. doi: 10.1586/14737140.7.12s.S23.
Glioblastoma multiforme (GBM) is the most aggressive of the infiltrating gliomas. Standards of care for treatment continue to evolve. In many westernized countries standard treatment of GBM at diagnosis includes surgery, radiotherapy and chemotherapy. In other parts of the world, chemotherapy that is considered beneficial by many is excluded from standard therapy, in large part due to issues of cost; treatment may be completely palliative, even limited to corticosteroid treatment alone. This review will focus on the current standard of care in the USA for newly diagnosed GBM, focusing on the evidence supporting that care.
多形性胶质母细胞瘤（GBM）是侵袭性最强的浸润性胶质瘤。治疗的护理标准不断发展。在许多西方国家，GBM诊断时的标准治疗包括手术、放疗和化疗。在世界其他地区，许多人认为有益的化疗被排除在标准治疗之外，很大程度上是由于成本问题；治疗可能完全是姑息性的，甚至仅限于单独使用皮质类固醇治疗。本综述将聚焦于美国新诊断GBM的当前护理标准，重点关注支持该护理的证据。
