Leibovici Vera, Alkalay Ronen, Hershko Klilah, Ingber Arieh, Westerman Maria, Leviatan-Strauss Nurith, Hochberg Malka
Department of Dermatology, Hadassah University Hospital, Jerusalem, Israel.
Mycoses. 2008 Jan;51(1):63-6. doi: 10.1111/j.1439-0507.2007.01443.x.
Data in the literature regarding the prevalence of Candida in psoriatic and atopic dermatitis patients are controversial. We conducted a prospective study to determine the prevalence of Candida on the tongue, axillae and groin of psoriatic patients when compared with atopic dermatitis patients and normal controls. During the period 2003-2005, data were collected from 100 psoriatic patients, 100 patients with atopic dermatitis and 100 normal controls. Fungal test specimens for Candida were collected from the axillae, groin and tongue of each patient. There was no increase in the prevalence of Candida in intertriginous area of either psoriatic or atopic dermatitis patients. However, the prevalence of Candida on the tongue was significantly higher in psoriatic patients (32%) compared with atopic dermatitis (18%) (P = 0.024) and higher, although not significantly, than in normal controls (21%) (P = 0.08). Our study did not reveal higher prevalence of Candida in the axillae and groin of either psoriatic or atopic dermatitis patients. There was a higher prevalence of Candida on the tongue of psoriatic patients. The Candida of the tongue was asymptomatic and did not correlate with age, gender, type of psoriasis or severity of the disease, therefore we conclude that this is clinically irrelevant.
文献中关于银屑病患者和特应性皮炎患者念珠菌感染率的数据存在争议。我们进行了一项前瞻性研究，以确定银屑病患者与特应性皮炎患者及正常对照组相比，其舌部、腋窝和腹股沟念珠菌的感染率。在2003年至2005年期间，收集了100例银屑病患者、100例特应性皮炎患者和100例正常对照组的数据。从每位患者的腋窝、腹股沟和舌部采集念珠菌真菌检测标本。银屑病患者或特应性皮炎患者间擦部位念珠菌感染率均未增加。然而，银屑病患者舌部念珠菌感染率（32%）显著高于特应性皮炎患者（18%）（P = 0.024），虽不显著高于正常对照组（21%）（P = 0.08）。我们的研究未发现银屑病患者或特应性皮炎患者腋窝和腹股沟念珠菌感染率更高。银屑病患者舌部念珠菌感染率更高。舌部念珠菌感染无症状，且与年龄、性别、银屑病类型或疾病严重程度无关，因此我们得出结论，这在临床上不相关。
