Thomas C, Matthies M, Homey B, Meller S
Klinik für Dermatologie, Medizinische Fakultät, Heinrich-Heine-Universität, Moorenstr. 5, 40225, Düsseldorf, Deutschland.
Hautarzt. 2020 Apr;71(4):263-268. doi: 10.1007/s00105-020-04558-7.
Intertriginous psoriasis is a variant of psoriasis that is associated with inflammatory lesions in skin folds. Patients often feel ashamed, are subjected to stigmatization, social isolation, or experience mental health issues. There is no general consensus on the definition of intertriginous psoriasis. Depending on the definition used, the prevalence varies substantially. Due to the particular location of skin lesions, therapeutic management is very challenging. Mild symptoms can be treated with topical corticosteroids or topical immunomodulators. There are encouraging data demonstrating the efficacy of ixekizumab, possibly charting the way for it to become a systemic treatment option.
间擦部位银屑病是银屑病的一种变体，与皮肤褶皱处的炎症性病变相关。患者常感到羞愧，遭受污名化、社会孤立，或出现心理健康问题。对于间擦部位银屑病的定义尚无普遍共识。根据所使用的定义，患病率差异很大。由于皮肤病变的特殊位置，治疗管理极具挑战性。轻度症状可用外用糖皮质激素或外用免疫调节剂治疗。有令人鼓舞的数据证明了司库奇尤单抗的疗效，这可能为其成为一种全身治疗选择指明方向。
