新生儿无乳链球菌败血症期间溶血素表达的异质性。
Heterogeneity of hemolysin expression during neonatal Streptococcus agalactiae sepsis.
作者信息
Sigge Anja, Schmid Manuel, Mauerer Stefanie, Spellerberg Barbara
机构信息
Institute of Medical Microbiology and Hygiene, Robert Koch Str. 8, Ulm D-89081, Germany.
出版信息
J Clin Microbiol. 2008 Feb;46(2):807-9. doi: 10.1128/JCM.01963-07. Epub 2007 Dec 12.
Abstract
The beta-hemolysin of Streptococcus agalactiae is a major virulence factor; consequently, nonhemolytic strains rarely cause infections. We report on a case of neonatal sepsis caused by a strain displaying heterogeneous hemolysin expression. It was detected by the simultaneous isolation of hemolytic and nonhemolytic colonies from cultures of the infant's blood.
摘要
无乳链球菌的β-溶血素是一种主要的毒力因子；因此，非溶血型菌株很少引起感染。我们报告了一例由表现出溶血素表达异质性的菌株引起的新生儿败血症病例。它是通过从婴儿血液培养物中同时分离出溶血和非溶血型菌落而检测到的。
相似文献
1
Heterogeneity of hemolysin expression during neonatal Streptococcus agalactiae sepsis.新生儿无乳链球菌败血症期间溶血素表达的异质性。
J Clin Microbiol. 2008 Feb;46(2):807-9. doi: 10.1128/JCM.01963-07. Epub 2007 Dec 12.
2
Transposon mutagenesis of group B streptococcus beta-hemolysin biosynthesis.B族链球菌β-溶血素生物合成的转座子诱变
Infect Immun. 1987 Sep;55(9):2314-6. doi: 10.1128/iai.55.9.2314-2316.1987.
3
Identification of genetic determinants for the hemolytic activity of Streptococcus agalactiae by ISS1 transposition.通过ISS1转座鉴定无乳链球菌溶血活性的遗传决定因素。
J Bacteriol. 1999 May;181(10):3212-9. doi: 10.1128/JB.181.10.3212-3219.1999.
4
5
Meningitis and bacteremia by nonhemolytic Group B Streptococcus strain: A whole genome analysis.非溶血性B族链球菌菌株引起的脑膜炎和菌血症：全基因组分析
Microbiol Immunol. 2020 Sep;64(9):630-634. doi: 10.1111/1348-0421.12826. Epub 2020 Jul 21.
6
Endocarditis caused by nonhemolytic group B streptococcus.非溶血性B组链球菌引起的心内膜炎。
J Clin Microbiol. 1997 Jun;35(6):1616-7. doi: 10.1128/jcm.35.6.1616-1617.1997.
7
The putative glycosyltransferase-encoding gene cylJ and the group B Streptococcus (GBS)-specific gene cylK modulate hemolysin production and virulence of GBS.推测的糖基转移酶编码基因cylJ和B族链球菌（GBS）特异性基因cylK调节GBS的溶血素产生和毒力。
Infect Immun. 2007 Apr;75(4):2063-6. doi: 10.1128/IAI.01565-06. Epub 2007 Feb 5.
8
Type IV neonatal early-onset group B streptococcal disease in a United States hospital.美国一家医院的IV型新生儿早发型B族链球菌病
J Clin Microbiol. 2007 Apr;45(4):1360-2. doi: 10.1128/JCM.02487-06. Epub 2007 Jan 31.
9
Non-haemolytic and non-pigmented group b streptococcus, an infrequent cause of early onset neonatal sepsis.非溶血性和无色素B族链球菌，早发型新生儿败血症的罕见病因。
Pathog Dis. 2015 Dec;73(9):ftv089. doi: 10.1093/femspd/ftv089. Epub 2015 Oct 7.
10
The R-proteins.
Antibiot Chemother (1971). 1985;35:114-8. doi: 10.1159/000410366.
引用本文的文献
1
Hemolytic Membrane Vesicles of Group B Streptococcus Promote Infection.B 群链球菌溶血膜囊泡促进感染。
J Infect Dis. 2021 Apr 23;223(8):1488-1496. doi: 10.1093/infdis/jiaa548.
2
Reliable Detection of Group B Streptococcus in the Clinical Laboratory.临床实验室中B族链球菌的可靠检测
J Clin Microbiol. 2017 Sep;55(9):2590-2598. doi: 10.1128/JCM.00582-17. Epub 2017 Jun 28.
3
Molecular Characterization of Nonhemolytic and Nonpigmented Group B Streptococci Responsible for Human Invasive Infections.导致人类侵袭性感染的非溶血性和无色素B族链球菌的分子特征
J Clin Microbiol. 2016 Jan;54(1):75-82. doi: 10.1128/JCM.02177-15. Epub 2015 Oct 21.
4
Non-haemolytic and non-pigmented group b streptococcus, an infrequent cause of early onset neonatal sepsis.非溶血性和无色素B族链球菌，早发型新生儿败血症的罕见病因。
Pathog Dis. 2015 Dec;73(9):ftv089. doi: 10.1093/femspd/ftv089. Epub 2015 Oct 7.
5
Group B streptococcal haemolysin and pigment, a tale of twins.B族链球菌溶血素与色素：一对孪生的故事
FEMS Microbiol Rev. 2014 Sep;38(5):932-46. doi: 10.1111/1574-6976.12071. Epub 2014 Apr 4.
6
Regulation of CovR expression in Group B Streptococcus impacts blood-brain barrier penetration.B 群链球菌 CovR 表达的调控影响血脑屏障穿透性。
Mol Microbiol. 2010 Jul;77(2):431-43. doi: 10.1111/j.1365-2958.2010.07215.x. Epub 2010 May 19.
7
Identification of an unusual pattern of global gene expression in group B Streptococcus grown in human blood.鉴定 B 群链球菌在人血液中生长时出现的一种不寻常的全基因表达模式。
PLoS One. 2009 Sep 23;4(9):e7145. doi: 10.1371/journal.pone.0007145.
8
Bacterial phenotype variants in group B streptococcal toxic shock syndrome.B族链球菌中毒性休克综合征中的细菌表型变异体。
Emerg Infect Dis. 2009 Feb;15(2):223-32. doi: 10.3201/eid1502.080990.
本文引用的文献
1
Transport of multidrug resistance substrates by the Streptococcus agalactiae hemolysin transporter.无乳链球菌溶血素转运体对多药耐药底物的转运
J Bacteriol. 2006 Aug;188(16):5984-92. doi: 10.1128/JB.00768-05.
2
Genetic diversity of the C protein beta-antigen gene and its upstream regions within clonally related groups of type Ia and Ib group B streptococci.Ia型和Ib型B族链球菌克隆相关组内C蛋白β抗原基因及其上游区域的遗传多样性。
Microbiology (Reading). 2006 Mar;152(Pt 3):771-778. doi: 10.1099/mic.0.28535-0.
3
Epidemiology of Streptococcus agalactiae colonization in Germany.德国无乳链球菌定植的流行病学
Int J Med Microbiol. 2006 Feb;296(1):39-44. doi: 10.1016/j.ijmm.2005.11.001. Epub 2005 Dec 19.
4
Differences in the DNA sequence of the translational attenuator of several constitutively expressed erm(A) genes from clinical isolates of Streptococcus agalactiae.来自无乳链球菌临床分离株的几种组成型表达erm(A)基因的翻译弱化子DNA序列差异。
J Antimicrob Chemother. 2005 Nov;56(5):836-40. doi: 10.1093/jac/dki337. Epub 2005 Sep 26.
5
Multiplex PCR assay for direct identification of group B streptococcal alpha-protein-like protein genes.用于直接鉴定B族链球菌α蛋白样蛋白基因的多重聚合酶链反应检测法
J Clin Microbiol. 2004 Mar;42(3):1326-9. doi: 10.1128/JCM.42.3.1326-1329.2004.
6
Multilocus sequence typing of serotype III group B streptococcus and correlation with pathogenic potential.B族链球菌血清型III的多位点序列分型及其与致病潜力的相关性。
J Infect Dis. 2004 Mar 15;189(6):1097-102. doi: 10.1086/382087. Epub 2004 Feb 27.
7
Multilocus sequence typing system for group B streptococcus.B族链球菌多位点序列分型系统
J Clin Microbiol. 2003 Jun;41(6):2530-6. doi: 10.1128/JCM.41.6.2530-2536.2003.
8
Prevention of perinatal group B streptococcal disease. Revised guidelines from CDC.预防围产期B族链球菌病。美国疾病控制与预防中心修订指南。
MMWR Recomm Rep. 2002 Aug 16;51(RR-11):1-22.
9
Serotype identification of group B streptococci by PCR and sequencing.通过聚合酶链反应（PCR）和测序对B族链球菌进行血清型鉴定。
J Clin Microbiol. 2002 Jan;40(1):216-26. doi: 10.1128/JCM.40.1.216-226.2002.
10
Analysis of restriction fragment length polymorphisms of the insertion sequence IS1381 in group B Streptococci.B族链球菌中插入序列IS1381的限制性片段长度多态性分析
J Infect Dis. 2000 Jan;181(1):364-8. doi: 10.1086/315205.
Zotero 插件