Makuwa Maria, Caron Mélanie, Souquière Sandrine, Malonga-Mouelet Gabriel, Mahé Antoine, Kazanji Mirdad
Laboratoire de Virologie, Centre International de Recherches Médicales, BP 769, Franceville, Gabon.
J Clin Microbiol. 2008 Feb;46(2):754-6. doi: 10.1128/JCM.02142-07. Epub 2007 Dec 12.
Hepatitis B virus (HBV) surface antigen (HBsAg) was found in 9.2% of 1,186 pregnant women from Gabon, of whom 10.1% had the HBe antigen and 89.9% had anti-HBe antibodies. Antibodies to the hepatitis delta virus (HDV) were found in 15.6% of the HBsAg-positive women. The HBV strains were of the A3 and E genotypes. The HDV strains belonged to HDV clades 1 and 8. These results provide clear evidence that HDV clade 8 is indigenous to Africa.
在加蓬1186名孕妇中,9.2%的人检测出乙肝病毒(HBV)表面抗原(HBsAg),其中10.1%的人有HBe抗原,89.9%的人有抗HBe抗体。在HBsAg阳性女性中,15.6%的人检测出丁型肝炎病毒(HDV)抗体。HBV毒株为A3和E基因型。HDV毒株属于HDV进化枝1和8。这些结果提供了明确证据,表明HDV进化枝8原产于非洲。