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通过核苷酸序列变异鉴别2型单纯疱疹病毒毒株

Discrimination of herpes simplex virus type 2 strains by nucleotide sequence variations.

作者信息

Kaneko Hisatoshi, Kawana Takashi, Ishioka Ken, Fukushima Eiko, Suzutani Tatsuo

机构信息

Department of Microbiology, Fukushima Medical University School of Medicine, Fukushima 960-1295, Japan.

出版信息

J Clin Microbiol. 2008 Feb;46(2):780-4. doi: 10.1128/JCM.01615-07. Epub 2007 Dec 12.

Abstract

We determined the polymorphous 400-bp regions in UL53, US1, and US4 for the discrimination of herpes simplex virus type 2 (HSV-2) strains. Thirty-six HSV-2 clinical strains could be differentiated into 35 groups using these three regions and into 36 groups by additional analysis of three noncoding regions previously reported as polymorphous.

摘要

我们确定了UL53、US1和US4中400bp的多态性区域,用于鉴别2型单纯疱疹病毒(HSV-2)毒株。利用这三个区域,36株HSV-2临床毒株可分为35组,通过对先前报道具有多态性的三个非编码区域进行额外分析,则可分为36组。

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