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通过核苷酸序列变异鉴别2型单纯疱疹病毒毒株

Discrimination of herpes simplex virus type 2 strains by nucleotide sequence variations.

作者信息

Kaneko Hisatoshi, Kawana Takashi, Ishioka Ken, Fukushima Eiko, Suzutani Tatsuo

机构信息

Department of Microbiology, Fukushima Medical University School of Medicine, Fukushima 960-1295, Japan.

出版信息

J Clin Microbiol. 2008 Feb;46(2):780-4. doi: 10.1128/JCM.01615-07. Epub 2007 Dec 12.

DOI:10.1128/JCM.01615-07
PMID:18077652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2238078/
Abstract

We determined the polymorphous 400-bp regions in UL53, US1, and US4 for the discrimination of herpes simplex virus type 2 (HSV-2) strains. Thirty-six HSV-2 clinical strains could be differentiated into 35 groups using these three regions and into 36 groups by additional analysis of three noncoding regions previously reported as polymorphous.

摘要

我们确定了UL53、US1和US4中400bp的多态性区域，用于鉴别2型单纯疱疹病毒（HSV-2）毒株。利用这三个区域，36株HSV-2临床毒株可分为35组，通过对先前报道具有多态性的三个非编码区域进行额外分析，则可分为36组。

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本文引用的文献

1
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J Clin Microbiol. 2006 Jul;44(7):2541-6. doi: 10.1128/JCM.00054-06.
2
Sensitive and rapid detection of herpes simplex virus and varicella-zoster virus DNA by loop-mediated isothermal amplification.通过环介导等温扩增技术灵敏快速地检测单纯疱疹病毒和水痘-带状疱疹病毒DNA
J Clin Microbiol. 2005 Jul;43(7):3290-6. doi: 10.1128/JCM.43.7.3290-3296.2005.
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Global identification of three major genotypes of varicella-zoster virus: longitudinal clustering and strategies for genotyping.水痘带状疱疹病毒三种主要基因型的全球鉴定：纵向聚类及基因分型策略
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