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[用卫非特、吡嗪酰胺、乙胺丁醇及手术治疗溃疡分枝杆菌感染：1例6年随访病例报告]

[Mycobacterium ulcerans infection treated by Rifater, pyrazynamide, Myambutol, and surgery: a case report with a 6-year follow-up].

作者信息

Kibadi K

机构信息

Département de Chirurgie, Cliniques Universitaires, Université de Kinshasa, Kinshasa XI, Democratic Republic of Congo.

出版信息

Med Mal Infect. 2008 Mar;38(3):156-8. doi: 10.1016/j.medmal.2007.09.009. Epub 2008 Feb 20.

DOI:10.1016/j.medmal.2007.09.009
PMID:18079081
Abstract

The author reports a case of pleuritis associated with a large homolateral Buruli thorax ulcer in a nine-year old female patient, in the Democratic Republic of Congo. Smears on Ziehl-Neelsen revealed acid-alcohol-resistant bacilli. The pathological histology confirmed a Mycobacterium ulcerans infection (Buruli ulcer). The treatment was surgical (excision-dressing-grafting) associated to antibiotic therapy (Rifater, Pyrazynamide, and Myambutol). After six years of follow up, no relapse was observed.

摘要

作者报告了刚果民主共和国一名9岁女性患者发生的胸膜炎病例，该患者患侧胸部有一个巨大的布鲁里溃疡。萋尼氏涂片显示抗酸杆菌。病理组织学证实为溃疡分枝杆菌感染（布鲁里溃疡）。治疗方法为手术治疗（切除-换药-植皮）联合抗生素治疗（卫非特、吡嗪酰胺和乙胺丁醇）。随访6年后，未观察到复发。

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