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Manganese-DPDP as a hepatobiliary contrast agent in the magnetic resonance imaging of liver tumors. Results of clinical phase II trials in Germany including 141 patients.

作者信息

Rummeny E, Ehrenheim C, Gehl H B, Hamm B, Laniado M, Lodemann K P, Schmiedel E, Steudel A, Vogl T G

机构信息

Department of Radiology, University of Muenster, Germany.

出版信息

Invest Radiol. 1991 Nov;26 Suppl 1:S142-5; discussion S150-5. doi: 10.1097/00004424-199111001-00048.

DOI:10.1097/00004424-199111001-00048
PMID:1808111
Abstract
摘要

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Manganese-DPDP as a hepatobiliary contrast agent in the magnetic resonance imaging of liver tumors. Results of clinical phase II trials in Germany including 141 patients.锰-二乙烯三胺五乙酸二异丙胺（Manganese-DPDP）作为肝脏肿瘤磁共振成像中的一种肝胆造影剂。德国141例患者的II期临床试验结果。
Invest Radiol. 1991 Nov;26 Suppl 1:S142-5; discussion S150-5. doi: 10.1097/00004424-199111001-00048.
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Contrast-enhanced magnetic resonance imaging of the liver with Mn-DPDP for known or suspected focal hepatic disease.使用锰-二吡啶二羧酸二钠对已知或疑似肝脏局灶性疾病进行肝脏对比增强磁共振成像。
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A segmental hyperintensity area in the liver shown by delayed MR images with Mn-DPDP.用锰-二吡啶二羧酸钆延迟磁共振成像显示肝脏中的节段性高信号区。
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Manganese (II) N,N'-dipyridoxylethylenediamine-N,N'-diacetate 5,5'-bis(phosphate): clinical experience with a new contrast agent.锰（II）N，N'-二吡啶氧基乙二胺-N，N'-二乙酸5,5'-双（磷酸酯）：一种新型造影剂的临床经验
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The need for effective contrast agents to enhance the performance of MR imaging.
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Mn-DPDP-enhanced MR imaging of malignant liver lesions: efficacy and safety in 20 patients.
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Pharmaceuticals (Basel). 2019 Sep 16;12(3):137. doi: 10.3390/ph12030137.
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Manganese-Enhanced Magnetic Resonance Imaging: Overview and Central Nervous System Applications With a Focus on Neurodegeneration.锰增强磁共振成像：概述及以神经退行性变研究为重点的中枢神经系统应用
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Theranostics and contrast agents for magnetic resonance imaging.
用于磁共振成像的诊疗剂与造影剂。
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Safety of MR liver specific contrast media.磁共振肝脏特异性对比剂的安全性
Eur Radiol. 2005 Aug;15(8):1607-14. doi: 10.1007/s00330-004-2612-x. Epub 2004 Dec 31.
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Hepatobiliary contrast agents for contrast-enhanced MRI of the liver: properties, clinical development and applications.用于肝脏对比增强磁共振成像的肝胆对比剂：特性、临床研发与应用
Eur Radiol. 2004 Apr;14(4):559-78. doi: 10.1007/s00330-004-2236-1. Epub 2004 Feb 25.