Kugelberg Maria, Wejde Gisela, Jayaram Hari, Zetterström Charlotta
Department of Clinical Neuroscience, St Erik's Eye Hospital, Karolinska Institute, Stockholm, Sweden.
Acta Ophthalmol. 2008 Aug;86(5):533-6. doi: 10.1111/j.1600-0420.2007.01094.x. Epub 2007 Dec 11.
To evaluate posterior capsule opacification (PCO) 2 years after cataract surgery following implantation of a hydrophilic or a hydrophobic single-piece acrylic intraocular lens (IOL) with a sharp edge.
Phacoemulsification cataract surgery was performed in one eye of 120 patients with senile cataract in this prospective study. They were randomized to implantation of either a hydrophilic acrylic IOL (BL27; Bausch & Lomb, Rochester, NY, USA) or a hydrophobic acrylic IOL (AcrySof) SA60AT; Alcon Laboratories, Fort Worth, TX, USA). Two years after surgery, retroillumination images were obtained and PCO area and severity were evaluated using pocoman software. Best corrected visual acuity (VA) (both high-contrast [100%] and low-contrast [2.5%]), glare, laser flare and intraocular pressure were measured. Capsulotomy rates were recorded.
Patients implanted with the hydrophilic IOL had a greater percentage area and severity of PCO compared with patients with the hydrophobic IOL (p < 0.001). There was no difference in PCO between men and women in the hydrophilic group. However, in the hydrophobic group, women had significantly more PCO than men (p < 0.05). Patients with the hydrophobic acrylic IOL had better high- and low-contrast visual activity (VA) (p < 0.01) and less glare (p < 0.001) than those with a hydrophilic acrylic IOL. Of the patients with the hydrophilic IOL, 42% underwent capsulotomy, compared with 10% in the hydrophobic group (p < 0.001).
Two years after surgery, patients with the SA60AT hydrophobic acrylic IOL had less PCO and better high- and low-contrast VA than patients with the BL27 hydrophilic acrylic IOL.
评估白内障手术后2年，植入具有锐边的亲水性或疏水性单片丙烯酸人工晶状体（IOL）后后囊膜混浊（PCO）的情况。
在这项前瞻性研究中，对120例老年性白内障患者的一只眼睛进行了超声乳化白内障手术。他们被随机分为植入亲水性丙烯酸IOL（BL27；美国纽约罗切斯特的博士伦公司）或疏水性丙烯酸IOL（AcrySof SA60AT；美国德克萨斯州沃思堡的爱尔康实验室公司）。手术后2年，获得了后照光图像，并使用pocoman软件评估PCO面积和严重程度。测量了最佳矫正视力（VA）（包括高对比度[100%]和低对比度[2.5%]）、眩光、激光散射和眼压。记录了囊切开术的发生率。
与植入疏水性IOL的患者相比，植入亲水性IOL的患者PCO的面积百分比和严重程度更高（p < 0.001）。亲水性组中男性和女性的PCO没有差异。然而，在疏水性组中，女性的PCO明显多于男性（p < 0.05）。与植入亲水性丙烯酸IOL的患者相比，植入疏水性丙烯酸IOL的患者具有更好的高对比度和低对比度视觉活动（VA）（p < 0.01）以及更少的眩光（p < 0.001）。植入亲水性IOL的患者中，42%接受了囊切开术，而疏水性组为10%（p < 0.001）。
手术后2年，与植入BL27亲水性丙烯酸IOL的患者相比，植入SA60AT疏水性丙烯酸IOL的患者PCO更少，高对比度和低对比度VA更好。
