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2
Long-term effect of sharp optic edges of a polymethyl methacrylate intraocular lens on posterior capsule opacification: a randomized trial.聚甲基丙烯酸甲酯人工晶状体锐利光学边缘对后囊膜混浊的长期影响：一项随机试验。
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Long-term effect of 1-piece and 3-piece hydrophobic acrylic intraocular lens on posterior capsule opacification: a randomized trial.一体式和三件式疏水丙烯酸人工晶状体对后囊膜混浊的长期影响：一项随机试验。
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本文引用的文献

1
Three-year incidence of Nd:YAG capsulotomy and posterior capsule opacification and its relationship to monofocal acrylic IOL biomaterial: a UK Real World Evidence study.钕钇铝石榴石激光晶状体囊切开术和后囊膜混浊的三年发病率及其与单焦点丙烯酸人工晶状体生物材料的关系：一项英国真实世界证据研究。
Eye (Lond). 2018 Oct;32(10):1579-1589. doi: 10.1038/s41433-018-0131-2. Epub 2018 Jun 11.
2
Causes of vision loss worldwide, 1990-2010: a systematic analysis.全球视力丧失的原因，1990-2010 年：一项系统分析。
Lancet Glob Health. 2013 Dec;1(6):e339-49. doi: 10.1016/S2214-109X(13)70113-X. Epub 2013 Nov 11.
3
Prevalence and causes of vision loss in high-income countries and in Eastern and Central Europe: 1990-2010.高收入国家以及东欧和中欧地区视力丧失的患病率及原因：1990 - 2010年
Br J Ophthalmol. 2014 May;98(5):629-38. doi: 10.1136/bjophthalmol-2013-304033. Epub 2014 Mar 24.
4
Posterior capsule opacification with 3 intraocular lenses: 12-year prospective study.三种人工晶状体导致的后囊膜混浊：12 年前瞻性研究。
J Cataract Refract Surg. 2014 Jan;40(1):70-6. doi: 10.1016/j.jcrs.2013.07.039. Epub 2013 Nov 14.
5
Three-year incidence and factors associated with posterior capsule opacification after cataract surgery: The Australian Prospective Cataract Surgery and Age-related Macular Degeneration Study.白内障手术后后囊膜混浊的 3 年发生率及相关因素：澳大利亚白内障手术与年龄相关性黄斑变性前瞻性研究。
Am J Ophthalmol. 2014 Jan;157(1):171-179.e1. doi: 10.1016/j.ajo.2013.08.016. Epub 2013 Oct 7.
6
Comparison of clinical efficacy: Nd:YAG laser rates after implantation of AcrySof® SN60WF, Akreos® AO-MI60 and Hoya® YA-60BB.临床疗效比较：植入AcrySof® SN60WF、Akreos® AO-MI60和Hoya® YA-60BB后的钕钇铝石榴石激光率。
J Fr Ophtalmol. 2013 Sep;36(7):575-82. doi: 10.1016/j.jfo.2012.07.008. Epub 2013 Apr 22.
7
Comparison of posterior capsule opacification and glistenings with 2 hydrophobic acrylic intraocular lenses: 5- to 7-year follow-up.两种疏水性丙烯酸人工晶状体术后后囊混浊和后囊膜混浊比较：5 至 7 年随访。
J Cataract Refract Surg. 2013 May;39(5):694-8. doi: 10.1016/j.jcrs.2012.11.032. Epub 2013 Mar 14.
8
Hydrophobic versus double-square-edged hydrophilic foldable acrylic intraocular lens: effect on posterior capsule opacification.疏水性与双双面亲水折叠式丙烯酸人工晶状体：对后囊混浊的影响。
J Cataract Refract Surg. 2011 Jun;37(6):1060-8. doi: 10.1016/j.jcrs.2010.12.059.
9
Comparison of posterior capsule opacification with hydrophobic acrylic and hydrophilic acrylic intraocular lenses.疏水丙烯酸和亲水丙烯酸人工晶状体后囊混浊的比较。
J Cataract Refract Surg. 2011 Jun;37(6):1050-9. doi: 10.1016/j.jcrs.2010.12.060.
10
Neodymium:YAG laser rates after bilateral implantation of hydrophobic or hydrophilic multifocal intraocular lenses: twenty-four month retrospective comparative study.双侧植入疏水或亲水多焦点人工晶状体后的钕钇铝石榴石激光发生率：24个月回顾性对照研究
J Cataract Refract Surg. 2010 Jul;36(7):1195-200. doi: 10.1016/j.jcrs.2010.01.027.

后囊膜混浊眼内植入物生物材料的影响及设计概述

An overview of the influence and design of biomaterial of the intraocular implant of the posterior capsule opacification.

作者信息

Nanu Razvan Vladimir, Ungureanu Emil, Instrate Sinziana Luminita, Vrapciu Alexandra, Cozubas Roxana, Carstocea Laura, Voinea Liliana Mary, Ciuluvica Radu

机构信息

"Sf Ioan" Emergency Hospital, Bucharest, Romania.

Ophthalmology Department, University Emergency Hospital; "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

出版信息

Rom J Ophthalmol. 2018 Jul-Sep;62(3):188-193.

PMID:30505987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6256071/
Abstract

Posterior capsule opacification remains till nowadays one of the most hypothetical problems concerning the cataract surgery. When it comes in preventing PCO, this complication is made in multiple ways that concern, along with the surgery steps, the choice for the biomaterial of the intraocular implant lens. The concern of influence of the type of the used material (hydro-phob/ hydro-philic), of the design of the implant (1-piece IOL = monobloc vs. 3 - piece IOL - multipiece) and with the design at the edge, they all have been considered in multiple studies. This article performs a synthesis of those studies and establishes conclusions regarding possible choices. PCO = Posterior capsule opacification, IOL = intraocular lens; LEC = lens epithelial cells.

摘要

后囊膜混浊至今仍是白内障手术中最具争议性的问题之一。在预防后囊膜混浊方面，这种并发症可通过多种方式引发，这不仅涉及手术步骤，还关乎眼内植入晶状体生物材料的选择。所使用材料的类型（疏水/亲水）、植入物的设计（一体式人工晶状体=整体式与三件式人工晶状体-多片式）以及边缘设计的影响等，在多项研究中均已得到考量。本文对这些研究进行了综述，并就可能的选择得出结论。PCO=后囊膜混浊，IOL=人工晶状体；LEC=晶状体上皮细胞