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[不同剂量冷却矿物油与杀菌剂刺激作用对兔皮肤影响的比较]

[Comparison of the effects of the irritant action of different amounts of cooling mineral oil with biocides on the rabbit skin].

作者信息

Nowak B, Małecka H, Miarczyńska-Jończyk H

机构信息

I Zakładu Higieny i Epidemiologii Slaskiej Akademii Medycznej w Katowicach.

出版信息

Med Pr. 1991;42(6):447-52.

PMID:1808453
Abstract

Effects of different concentrations of Emulgol EN-BIO C/88 oil on rabbit skin were studied. Experiments were carried out to examine oil irritancy to the skin and the inner surface of the ear skin subjected to a 24-hour closed exposure and repeated open exposure for 10 days, respectively. The data obtained have shown that 5 and 10 per cent emulsions of Emulgol EN-BIO C/88 produce mild skin irritation, while a 50 per cent emulsion and concentrate cause irritation of moderate degree. This means that the irritating potential of Emulgol depends on its concentration in oil-water emulsion. It is concluded that EN-BIO C/88 oil should be used in a 5 per cent concentration in industry.

摘要

研究了不同浓度的Emulgol EN - BIO C/88油对兔皮肤的影响。分别进行实验,检测该油对皮肤以及耳内皮肤表面的刺激性,分别进行24小时封闭暴露和连续10天的反复开放性暴露。所获得的数据表明,5%和10%的Emulgol EN - BIO C/88乳液会产生轻度皮肤刺激,而50%的乳液和浓缩液会引起中度刺激。这意味着Emulgol的刺激潜力取决于其在油水乳液中的浓度。得出结论,工业上应使用5%浓度的EN - BIO C/88油。

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