Quinio Caroline, Biltoft-Jensen Anja, De Henauw Stefaan, Gibney Michael J, Huybrechts Inge, McCarthy Sinéad N, O'Neill Jennifer L, Tetens Inge, Turrini Aida, Volatier Jean-Luc
French Food Safety Agency - AFSSA, Paris, France.
Eur J Nutr. 2007 Dec;46 Suppl 2:37-46. doi: 10.1007/s00394-007-2005-4.
A new EU regulation on nutrition and health claims made on foods has entered into force in January 2007. The regulation provides for the use of nutrient profiles to determine which foods may bear claims but does not specify what the profiles should be or how they should be developed. Several nutrient profiling schemes have already been established. Therefore, it is necessary to develop approaches to test if the existing profiling schemes could fulfil the new regulation needs. The aim of the present study is to investigate how reference "indicator foods" derived from national dietary surveys in five different countries, are classified according to three existing nutrient profiling schemes: The UK Food Standards Agency (FSA) model, The Dutch Tripartite classification model and the US FDA model used for regulating health claims. "Indicator foods" that have been shown to be positively or negatively associated with healthy diets in adults in five EU countries were classified according to each of the three profiling schemes. The performance and effectiveness of each profiling scheme in correctly classifying the "indicator foods" were assessed using sensitivity and specificity ratios. The sensitivity and the specificity ratios of the three profiling schemes tested were relatively good. There were only small differences of performance between the three systems. A significant negative correlation between sensitivity and specificity was observed. The level of concordance between the classification of the "indicator foods" that have been selected because of being positively or negatively associated with a healthy diet and the classification by each of the three profiling methods tested was quite good. However, further improvement of the "indicator foods" approach is needed if it is to serve as a "gold standard".
欧盟一项关于食品营养与健康声称的新法规于2007年1月生效。该法规规定利用营养成分表来确定哪些食品可以做出声称,但未具体说明营养成分表应该是怎样的,以及应如何制定。目前已经建立了几种营养成分分析方案。因此,有必要开发方法来测试现有的分析方案是否能够满足新法规的要求。本研究的目的是调查从五个不同国家的国民膳食调查中得出的参考“指示性食品”,根据三种现有的营养成分分析方案如何分类:英国食品标准局(FSA)模型、荷兰三方分类模型以及美国食品药品监督管理局(FDA)用于规范健康声称的模型。已证明在五个欧盟国家与成年人健康饮食呈正相关或负相关的“指示性食品”,根据这三种分析方案中的每一种进行分类。使用灵敏度和特异度比率评估每种分析方案在正确分类“指示性食品”方面的性能和有效性。所测试的三种分析方案的灵敏度和特异度比率相对较好。这三个系统之间的性能只有微小差异。观察到灵敏度和特异度之间存在显著的负相关。因与健康饮食呈正相关或负相关而被选中的“指示性食品”的分类与所测试的三种分析方法中的每一种的分类之间的一致性水平相当高。然而,如果要将“指示性食品”方法用作“金标准”,则需要进一步改进。