Shovadaeva G A, Shubin F N, Shaginian I A, Markov A P, Gintsburg A L, Smirnov G B
Mol Gen Mikrobiol Virusol. 1991 Nov(11):23-7.
The chromosomal DNA regions in Yersinia pseudotuberculosis strains occur that are homologous to 25 Md DNA segment of the plasmid pVM82 encoding the bacterial capability of immunosuppression. The character of the chromosomal DNA regions dispersion reacting with the 25 Md segment probes is different in epidemiologically hazardous and nonvirulent strains of Yersinia pseudotuberculosis. The specific DNA regions occur as well as identical ones. The suppression of antibody formation to a number of main Yersinia pseudotuberculosis antigens by epidemiologically hazardous strain is demonstrated. The suppression is analogous to the one previously described for Yersinia pseudotuberculosis strains harbouring the plasmid pVM82.
在假结核耶尔森氏菌菌株中存在与编码细菌免疫抑制能力的质粒pVM82的25 Md DNA片段同源的染色体DNA区域。在具有流行病学危险性的假结核耶尔森氏菌菌株和无毒菌株中，与25 Md片段探针发生反应的染色体DNA区域的分散特征有所不同。既存在特定的DNA区域，也存在相同的区域。具有流行病学危险性的菌株对多种主要假结核耶尔森氏菌抗原的抗体形成具有抑制作用。这种抑制作用与先前针对携带质粒pVM82的假结核耶尔森氏菌菌株所描述的抑制作用类似。
