Osaki Toshihiro, Nakagawa Makoto
Department of Chest Surgery, Saiseikai Fukuoka General Hospital, Fukuoka, Japan.
Surg Today. 2008;38(1):52-5. doi: 10.1007/s00595-007-3566-9. Epub 2007 Dec 24.
We report a case of a multilocular anterior mediastinal cyst with rim calcification and severe adhesion to the adjacent organs. We excised the cyst completely, with resection of the left phrenic nerve, pericardium, and left lung because of the severe adhesion. Histological examination revealed that the multilocular cystic walls were composed of fibrous connective tissue and calcifications, but the lining epithelial cells were absent because of dystrophic calcification resulting from chronic inflammation. On the basis of the location and pathological findings, we diagnosed a multilocular mediastinal cystic tumor; most likely a multilocular thymic cyst. It is important to distinguish a multilocular thymic cyst from a unilocular thymic cyst because a multilocular thymic cyst may recur postoperatively and coexist with a thymic epithelial tumor. Dense adhesion to the surrounding mediastinal structures may make removal difficult, especially if there is rim calcification.
我们报告一例多房性前纵隔囊肿,伴有边缘钙化且与相邻器官严重粘连。由于粘连严重,我们完整切除了囊肿,同时切除了左膈神经、心包和左肺。组织学检查显示,多房性囊壁由纤维结缔组织和钙化构成,但由于慢性炎症导致的营养不良性钙化,内衬上皮细胞缺失。根据病变部位和病理结果,我们诊断为多房性纵隔囊性肿瘤;很可能是多房性胸腺囊肿。将多房性胸腺囊肿与单房性胸腺囊肿区分开来很重要,因为多房性胸腺囊肿术后可能复发,并与胸腺上皮肿瘤共存。与周围纵隔结构的致密粘连可能导致切除困难,尤其是存在边缘钙化时。