Ayed I A, Dafalla R, Yagi A I, Adam S E
Department of Veterinary Medicine, Pharmacology and Toxicology, University of Khartoum, Sudan.
Vet Hum Toxicol. 1991 Dec;33(6):557-60.
Ochratoxin A was fed at 0.5 ppm to Lohmann-type chicks from 7 d of age for 4 w. Body weights and efficiency of feed utilization were depressed and the activity of serum SDH and GDH and the concentration of uric acid were significantly increased. The concentration of serum total protein and potassium and Hb, PCV, RBC and WBC were significantly decreased in the test group. Lesions were seen in vital organs, with hemorrhage in the thigh. A slow recovery in the kidney was observed 3 w after removal from the experimental diet.
从7日龄起,以0.5 ppm的剂量给罗曼型雏鸡喂食赭曲霉毒素A,持续4周。雏鸡体重和饲料利用率降低,血清SDH和GDH活性以及尿酸浓度显著升高。试验组血清总蛋白、钾、血红蛋白、红细胞压积、红细胞和白细胞浓度显著降低。重要器官出现病变,大腿有出血。从实验日粮中移除后3周,观察到肾脏恢复缓慢。