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英国内分泌学免疫分析外部质量评估计划

UK external quality assessment scheme for immunoassays in endocrinology.

作者信息

MacKenzie F, Bullock D G, Ratcliffe J G

机构信息

UK EQAS for Thyroid-related Hormones, Wolfson Research Laboratories, Queen Elizabeth Hospital, Birmingham, UK.

出版信息

Ann Ist Super Sanita. 1991;27(3):453-7.

PMID:1809064
Abstract

UK EQAS provide the UK with a comprehensive system for EQA in endocrinology, as well as in other aspects of clinical chemistry and laboratory medicine. UK EQAS in endocrinology are scientifically designed to yield an objective assessment of participants' performance and stimulate improvements in between-laboratory agreement. The design uses appropriate specimens, based on liquid human serum and prepared with minimal processing and additives in the organising centres to enable detailed study of recovery and other important factors. Target values are validated by reproducibility on repeated distribution and by recovery and parallelism studies. Reports are presented informatively, and emphasise the cumulative scoring system (bias and variance) for performance assessment. Computerised data processing and data presentation form an integral part of these schemes, and a common core computing system is in use throughout these UK EQAS. Participants receive advice and assistance in the interpretation of performance data and, when appropriate, in the resolution of problems.

摘要

英国内分泌质量评估计划(UK EQAS)为英国提供了一个全面的内分泌学以及临床化学和检验医学其他方面的质量评估体系。英国内分泌质量评估计划在科学设计上能够对参与者的表现进行客观评估,并促进实验室间一致性的改进。该设计使用基于液态人血清的合适标本,在组织中心以最少的处理和添加剂进行制备,以便能够详细研究回收率及其他重要因素。通过对重复分布的再现性以及回收率和平行性研究来验证靶值。报告以信息丰富的方式呈现,并强调用于性能评估的累积评分系统(偏差和方差)。计算机化的数据处理和数据呈现是这些计划不可或缺的一部分,并且在整个英国内分泌质量评估计划中使用一个通用的核心计算系统。参与者在性能数据解释以及在适当情况下解决问题方面会得到建议和帮助。

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