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使用布里斯临床评分系统诊断A组β溶血性链球菌

Diagnosis of group A beta-hemolytic Streptococcus using the Breese clinical scoring system.

作者信息

Karacan Mehmet, Karakelleoğlu Cahit, Orbak Zerrin

机构信息

Atatürk University, Faculty of Medicine, Department of Pediatric Endocrinology, Erzurum, Turkey.

出版信息

South Med J. 2007 Dec;100(12):1192-7. doi: 10.1097/SMJ.0b013e31815a94a8.

Abstract

This study was planned to determine the effectiveness of the Breese scoring system for the diagnosis of streptococcal pharyngitis and to evaluate its significance in different age groups. The research population was divided into two age groups. Group 1 consisted of children aged three and below and group 2 comprised children over three years of age. All of them were then evaluated using both the Breese scoring system and throat swab cultures. In group 1, there was no difference between the mean Breese scores of group A beta-hemolytic Streptococcus (GABHS)-positive and negative patients. However, in group 2, the mean Breese scores were higher in GABHS-positive patients than in GABHS-negative patients (P < 0.001). The diagnostic value of the Breese scoring system in group 1 was sensitivity, 3.4%; specificity, 93.6%; positive predictive value, 18.2%; and negative predictive value, 70.1%. In group 2, sensitivity was 68.8%; specificity, 82.5%; positive predictive value, 78.8%; and negative predictive value, 73.7%. The results indicate that the Breese scoring system is still a useful scoring system for streptococcal pharyngitis in children over three years of age, and may help in deciding whether or not to take a throat-swab culture. A score >29 can be used as an indication for antibiotherapy. So it seems to be a useful marker for decision-making regarding antibiotherapy in emergency departments.

摘要

本研究旨在确定布里斯评分系统对诊断链球菌性咽炎的有效性,并评估其在不同年龄组中的意义。研究人群分为两个年龄组。第1组由三岁及以下儿童组成,第2组由三岁以上儿童组成。然后使用布里斯评分系统和咽拭子培养对所有儿童进行评估。在第1组中,A组β溶血性链球菌(GABHS)阳性和阴性患者的平均布里斯评分没有差异。然而,在第2组中,GABHS阳性患者的平均布里斯评分高于GABHS阴性患者(P<0.001)。布里斯评分系统在第1组中的诊断价值为:敏感性3.4%;特异性93.6%;阳性预测值18.2%;阴性预测值70.1%。在第2组中,敏感性为68.8%;特异性为82.5%;阳性预测值为78.8%;阴性预测值为73.7%。结果表明,布里斯评分系统对于三岁以上儿童的链球菌性咽炎仍是一个有用的评分系统,可能有助于决定是否进行咽拭子培养。评分>29可作为抗生素治疗的指征。因此,它似乎是急诊科抗生素治疗决策的一个有用指标。

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