Delis Spiros G, Touloumis Zisis, Bakoyiannis Andreas, Tassopoulos Nikos, Paraskeva Konstantina, Athanassiou Kostas, Safioleas Michael, Dervenis Christos
Liver Surgical Unit, Agia Olga Hospital, Athens, Greece.
Eur J Gastroenterol Hepatol. 2008 Jan;20(1):10-4. doi: 10.1097/MEG.0b013e3282f16a76.
Intrahepatic biliary cystadenoma (IBC) is a rare liver tumour, which has strong tendency to recur and malignant potential as it can progress to cystadenocarcinoma (IBCa).
From June 2003 to December 2006, four patients diagnosed with hepatic cystadenoma were operated on our Liver Surgical Unit. All patients were females with median age of 51 years (range 45-63 years). Liver resections included three left and one right hepatectomies. In two patients, IBC was diagnosed by abdominal imaging and serum tumour markers but the rest of the patients were initially misdiagnosed as simple cysts, treated by laparoscopic fenestration and referred to our unit after cyst recurrence.
In all cases, the pathology report was consistent with liver cystadenomas. The postoperative course was uneventful and the median hospital stay was 8 days (range 5-12 days). In a median 18-month follow-up (range 2-40 months), all patients are alive and free of recurrence.
Liver cystadenomas can be easily misdiagnosed with other hepatic cystic lesions. An aggressive surgical approach is recommended, due to their malignant potential and high recurrence rate after fenestration.
肝内胆管囊腺瘤（IBC）是一种罕见的肝脏肿瘤，具有很强的复发倾向和恶变潜能，可进展为囊腺癌（IBCa）。
2003年6月至2006年12月，4例诊断为肝囊腺瘤的患者在我们的肝脏外科接受手术。所有患者均为女性，中位年龄51岁（范围45 - 63岁）。肝切除术包括3例左半肝切除和1例右半肝切除。2例患者通过腹部影像学检查和血清肿瘤标志物诊断为IBC，其余患者最初被误诊为单纯囊肿，接受腹腔镜开窗引流治疗，囊肿复发后转诊至我院。
所有病例的病理报告均符合肝囊腺瘤。术后病程顺利，中位住院时间为8天（范围5 - 12天）。中位随访18个月（范围2 - 40个月），所有患者均存活且无复发。
肝囊腺瘤容易与其他肝囊性病变误诊。由于其恶变潜能和开窗引流后高复发率，建议采取积极的手术方法。
