Chiappa Gaspar R, Roseguini Bruno T, Alves Cristiano N, Ferlin Elton L, Neder J Alberto, Ribeiro Jorge P
Exercise Pathophysiology Research Laboratory, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil.
Med Sci Sports Exerc. 2008 Jan;40(1):111-6. doi: 10.1249/mss.0b013e3181591de1.
It has long been suggested that inspiratory muscle activity may impact blood lactate levels ([Lac(-)]B) during the recovery from dynamic exercise. In this study, we tested the hypothesis that inspiratory muscle activation during recovery from intense exercise would contribute to La clearance, thus leading to reduced [Lac(-)]B.
Twelve healthy men underwent two maximal, incremental exercise tests on different days. During a 20-min inactive recovery period, they breathed freely or against a fixed inspiratory resistance of 15 cm H2O. During recovery, pulmonary gas exchange was continuously monitored, and serial samples of arterialized venous blood were obtained for [Lac(-)]B, pH, PCO2, and HCO3(-).
Subjects presented similar ventilatory and gas-exchange responses at peak exercise during both experimental conditions. [Lac(-)]B during recovery was reduced with inspiratory resistance (7.7 +/- 1 vs 10.4 +/- 1, 7.8 +/- 2 vs 10.3 +/- 2, and 7.3 +/- 1 vs 9.7 +/- 2 mM at 5, 7, and 9 min of recovery, respectively; P < 0.05), but no differences were found for blood acid-base status. Inspiratory resistance was associated with increased metabolic demand (V O2 and V CO2) but improved ventilatory efficiency, with lower V E/[V CO2] and increased alveolar ventilation.
These data are consistent with the notion that inspiratory muscles may be net consumers of lactate during recovery from intense exercise.
长期以来，人们一直认为吸气肌活动可能会影响动态运动恢复过程中的血乳酸水平（[Lac(-)]B）。在本研究中，我们检验了这样一个假设，即剧烈运动恢复期间的吸气肌激活有助于乳酸清除，从而导致[Lac(-)]B降低。
12名健康男性在不同日期进行了两次最大递增运动试验。在20分钟的非活动恢复期内，他们自由呼吸或对抗15 cm H2O的固定吸气阻力呼吸。在恢复过程中，持续监测肺气体交换，并采集动脉化静脉血系列样本以测定[Lac(-)]B、pH、PCO2和HCO3(-)。
在两种实验条件下，受试者在运动峰值时呈现出相似的通气和气体交换反应。恢复期间的[Lac(-)]B在有吸气阻力时降低（恢复5、7和9分钟时分别为7.7±1 vs 10.4±1、7.8±2 vs 10.3±2和7.3±1 vs 9.7±2 mM；P<0.05），但血酸碱状态无差异。吸气阻力与代谢需求增加（V O2和V CO2）相关，但通气效率提高，V E/[V CO2]降低，肺泡通气增加。
这些数据与以下观点一致，即吸气肌在剧烈运动恢复期间可能是乳酸的净消耗者。
