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用于隐形眼镜佩戴的视频速率和三维成像的光谱光学相干断层扫描技术

Spectral optical coherence tomography in video-rate and 3D imaging of contact lens wear.

作者信息

Kaluzny Bartlomiej J, Fojt Wojciech, Szkulmowska Anna, Bajraszewski Tomasz, Wojtkowski Maciej, Kowalczyk Andrzej

机构信息

Department of Ophthalmology, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.

出版信息

Optom Vis Sci. 2007 Dec;84(12):1104-9. doi: 10.1097/OPX.0b013e31815b9e0e.

DOI:10.1097/OPX.0b013e31815b9e0e
PMID:18091301
Abstract

PURPOSE

To present the applicability of spectral optical coherence tomography (SOCT) for video-rate and three-dimensional imaging of a contact lens on the eye surface.

METHODS

The SOCT prototype instrument constructed at Nicolaus Copernicus University (Torun, Poland) is based on Fourier domain detection, which enables high sensitivity (96 dB) and increases the speed of imaging 60 times compared with conventional optical coherence tomography techniques. Consequently, video-rate imaging and three-dimensional reconstructions can be achieved, preserving the high quality of the image. The instrument operates under clinical conditions in the Ophthalmology Department (Collegium Medicum Nicolaus Copernicus University, Bydgoszcz, Poland). A total of three eyes fitted with different contact lenses were examined with the aid of the instrument. Before SOCT measurements, slit lamp examinations were performed.

RESULTS

Data, which are representative for each imaging mode, are presented. The instrument provided high-resolution (4 microm axial x 10 microm transverse) tomograms with an acquisition time of 40 micros per A-scan. Video-rate imaging allowed the simultaneous quantitative evaluation of the movement of the contact lens and assessment of the fitting relationship between the lens and the ocular surface. Three-dimensional scanning protocols further improved lens visualization and fit evaluation.

CONCLUSIONS

SOCT allows video-rate and three-dimensional cross-sectional imaging of the eye fitted with a contact lens. The analysis of both imaging modes suggests the future applicability of this technology to the contact lens field.

摘要

目的

介绍光谱光学相干断层扫描(SOCT)在眼表隐形眼镜视频速率和三维成像方面的适用性。

方法

在哥白尼大学(波兰托伦)构建的SOCT原型仪器基于傅里叶域检测,具有高灵敏度(96 dB),与传统光学相干断层扫描技术相比,成像速度提高了60倍。因此,可以实现视频速率成像和三维重建,同时保持图像的高质量。该仪器在波兰比得哥什哥白尼大学医学院眼科的临床条件下运行。借助该仪器共检查了三只佩戴不同隐形眼镜的眼睛。在进行SOCT测量之前,先进行了裂隙灯检查。

结果

展示了每种成像模式的代表性数据。该仪器提供了高分辨率(轴向4微米×横向10微米)断层图像,每次A扫描的采集时间为40微秒。视频速率成像允许同时对隐形眼镜的运动进行定量评估,并评估镜片与眼表之间的适配关系。三维扫描方案进一步改善了镜片的可视化和适配评估。

结论

SOCT允许对佩戴隐形眼镜的眼睛进行视频速率和三维横截面成像。对这两种成像模式的分析表明该技术在隐形眼镜领域具有未来适用性。

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