Métro Thomas-Xavier, Pardo Domingo Gomez, Cossy Janine
Laboratoire de Chimie Organique, ESPCI, CNRS, 10 rue Vauquelin, 75231 Paris Cedex 05, France.
J Org Chem. 2008 Jan 18;73(2):707-10. doi: 10.1021/jo701554h. Epub 2007 Dec 20.
The formal total synthesis of (S,S)-reboxetine has been realized by two different approaches using a stereospecific rearrangement of beta-amino alcohols catalyzed by (CF3CO)2O.