Wheeler Derek S, Dent Catherine L, Manning Peter B, Nelson David P
Divisions of Critical Care Medicine, Cardiology, and Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Cardiol Young. 2008 Feb;18(1):41-50. doi: 10.1017/S1047951107001746. Epub 2007 Dec 20.
The arterial switch operation has become the preferred procedure for surgical management of transposition, defined on the basis of concordant atrioventricular and discordant ventriculo-arterial connections. We conducted a retrospective evaluation of our experience in 61 infants with this segmental combination, seen from January, 1997, to July, 2003, in order to determine the factors that are associated with a prolonged postoperative course. Factors independently associated with a prolonged postoperative stay in the cardiac intensive care unit included prematurity, difficulty in feeding, capillary leak, need for preoperative inotropic support, and postoperative infectious complications. Future research is warranted designed to minimize the impact of capillary leak and postoperative infectious complications. In addition, based on these results, our practice has evolved to initiate enteral feedings in the preoperative period if feasible, with such enteral feedings resumed as soon as possible following surgery.
动脉调转术已成为大动脉转位外科治疗的首选术式,其定义为房室连接一致而心室-动脉连接不一致。我们对1997年1月至2003年7月间收治的61例具有这种节段组合的婴儿的治疗经验进行了回顾性评估,以确定与术后病程延长相关的因素。与术后在心脏重症监护病房停留时间延长独立相关的因素包括早产、喂养困难、毛细血管渗漏、术前需要使用正性肌力药物支持以及术后感染并发症。有必要开展进一步研究,以尽量减少毛细血管渗漏和术后感染并发症的影响。此外,基于这些结果,我们的做法已演变为在可行的情况下于术前开始肠内喂养,并在术后尽快恢复肠内喂养。