Tang Monica, Russell Pamela J, Khatri Aparajita
Oncology Research Centre, Prince of Wales Hospital, Level 2, Clinical Sciences Building, Barker St., Randwick, NSW 2031, Australia.
Discov Med. 2007 Jun;7(38):68-74.
Nanotechnology based on the use of submicronic particles of inorganic and/or organic origin has the potential to revolutionalize the clinical management of cancer; the possibility of real time monitoring of disease progression and effects of therapy is now real. Especially, iron oxide super paramagnetic nanoparticles have shown clinical utility in cancer imaging and drug delivery and some formulations are now FDA-approved for use in the clinic. The prospects of magnetic nanoparticles in cancer imaging and treatment are reviewed.
基于使用无机和/或有机来源的亚微米颗粒的纳米技术有潜力彻底改变癌症的临床管理；实时监测疾病进展和治疗效果的可能性现在已经成为现实。特别是，氧化铁超顺磁性纳米颗粒已在癌症成像和药物递送中显示出临床应用价值，一些制剂现已获得美国食品药品监督管理局（FDA）批准用于临床。本文综述了磁性纳米颗粒在癌症成像和治疗方面的前景。
