Höke Ahmet, Mi Ruifa
Departments of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Discov Med. 2007 Aug;7(39):109-12.
Currently, we do not have effective therapies aimed at preventing or reversing axonal degeneration seen in peripheral neuropathies. Drug development programs should be aimed at understanding mechanisms of distal axonal degeneration and take into account the critical role Schwann cells play in axonal maintenance and nerve regeneration.
目前,我们没有针对预防或逆转周围神经病变中所见轴突变性的有效疗法。药物研发计划应旨在了解远端轴突变性的机制,并考虑到施万细胞在轴突维持和神经再生中所起的关键作用。