Gallagher R M, Marbach J J, Raphael K G, Dohrenwend B P, Cloitre M
Department of Psychiatry and Behavioral Sciences, State University of New York, Stony Brook 11794-8101.
Clin J Pain. 1991 Sep;7(3):219-25. doi: 10.1097/00002508-199109000-00008.
There is a lack of information about the precise strength of the relationship between chronic pain and depression. In a prior study, women with temporomandibular pain and dysfunction syndrome (TMPDS) had much higher scores than did controls on a measure of nonspecific psychological distress. The question arose as to whether rates of clinical depression are also unusually high in TMPDS patients. Their former treating clinician rates cases for likely lifetime presence or absence of depression. A subset of those rated as likely depressed then had their diagnoses verified independently through a structured clinical interview by a psychiatrist and clinical psychologist. Results revealed a minimum lifetime prevalence rate for major depression of 41%. A rate of this magnitude in TMPDS cases is clearly much higher than would be found for women of similar background in the general population.
关于慢性疼痛与抑郁症之间关系的确切强度，目前缺乏相关信息。在之前的一项研究中，患有颞下颌疼痛和功能障碍综合征（TMPDS）的女性在非特异性心理困扰测量中的得分比对照组高得多。于是出现了一个问题，即TMPDS患者的临床抑郁症发病率是否也异常高。他们之前的治疗医生对可能终生患抑郁症的情况进行评级。然后，那些被评定为可能患有抑郁症的患者中的一部分，由精神科医生和临床心理学家通过结构化临床访谈独立核实其诊断。结果显示，重度抑郁症的最低终生患病率为41%。在TMPDS病例中，这样的患病率明显高于在一般人群中具有相似背景的女性。
