Marques Marcelo Lorenzi, D'Alessandro Gabriel Salum, Chade Daher Cezar, Lanzoni Valéria Pereira, Saiovici Samuel, Almeida Cláudio José Ramos de
Hospital Professor Edmundo Vasconcelos, São Paulo, Brazil.
Sao Paulo Med J. 2007 Sep 6;125(5):297-9. doi: 10.1590/s1516-31802007000500011.
Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often difficult to morphologically distinguish them from metastatic colorectal adenocarcinoma.
We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of digestive tract tumor and for confirmation that it was a primary bladder tumor, an immunohistochemistry study was performed.
膀胱原发性腺癌并不常见，通常通过与其他腺癌（如结直肠癌、前列腺癌和妇科癌症）的连续性或血行播散而发生。黏液性和印戒细胞组织学模式更为罕见，并且在形态学上常常难以将它们与转移性结直肠腺癌区分开来。
我们展示并讨论了一名57岁男性患者的罕见膀胱原发性黏液性腺癌伴印戒细胞的病例。已排除肿瘤的其他原发部位，并且在没有消化道肿瘤的情况下，为了证实这是原发性膀胱肿瘤，进行了免疫组织化学研究。
