Singh Iqbal, Prasad Ravi
Consultant Urologist, Professor, Department of Surgery (Urology Div), University College of Medical Sciences (University of Delhi) & GTB Hospital , Delhi-110095 .
J Clin Diagn Res. 2013 May;7(5):911-3. doi: 10.7860/JCDR/2013/5597.2973. Epub 2013 May 1.
Urinary bladder cancer is the second most frequent tumour of the genitourinary tract with bladder adenocarcinoma comprising for about 0.5-2% of all malignant bladder tumours. Other primary sites for such tumours include rectum, stomach, endometrium, breast, prostate, seminal vesicles and ovaries. Such non-urothelial bladder tumours with intramural bladder tumour growth may delay the onset of symptoms which may lead to a delay in the diagnosis and thereby adversely affecting the prognosis as compared to urothelial bladder tumours. Traditionally bladder adenocarcinomas were believed to be resistant to both chemotherapy and radiotherapy, but recent advancements have shown encouraging responses with adjuvant chemotherapy and radiotherapy. We present here a case of primary urachal mucinous adenocarcinoma of the urinary bladder highlighting their relative rarity of occurrence and the difficulties encountered in diagnosing primary bladder mucinous adenocarcinoma.
膀胱癌是泌尿生殖道中第二常见的肿瘤，膀胱腺癌约占所有恶性膀胱肿瘤的0.5 - 2%。这类肿瘤的其他原发部位包括直肠、胃、子宫内膜、乳腺、前列腺、精囊和卵巢。这类具有膀胱壁内肿瘤生长的非尿路上皮膀胱肿瘤可能会延迟症状的出现，这可能导致诊断延迟，从而与尿路上皮膀胱肿瘤相比，对预后产生不利影响。传统上，膀胱腺癌被认为对化疗和放疗均耐药，但最近的进展表明辅助化疗和放疗有令人鼓舞的反应。我们在此介绍一例原发性膀胱脐尿管黏液腺癌病例，突出其发生相对罕见以及诊断原发性膀胱黏液腺癌时遇到的困难。
