Sigalas Konstantinos, Tyritzis Stavros I, Trigka Eleni, Katafigiotis Ioannis, Kavantzas Nikolaos, Stravodimos Konstantinos G
Department of Urology, Athens University Medical School-LAIKO Hospital, Athens, Greece.
Cases J. 2010 Feb 3;3:49. doi: 10.1186/1757-1626-3-49.
The primary mucinous adenocarcinoma of the bladder is an extremely rare urologic entity, which is found in less than 2% of all urinary bladder tumours and is often presented as metastatic.
A 69-year old male patient was diagnosed with a primary mucinous adenocarcinoma of the bladder after undergoing a transurethral resection of a bladder tumour and complete examination of the entire gastrointestinal tract to rule out other primary cites. Immunohistochemistry confirmed the nature of the tumour. The patient underwent a radical cystoprostatectomy with en block bilateral pelvic lymphadenectomy and urinary diversion with a Bricker ileostomy.
The primary adenocarcinoma creates a diagnostic dilemma, since it cannot be easily differentiated by the adenocarcinoma that originates from the colon and the prostate. We advocate the radical surgical management, after exclusion of any primary malignant sites related to the gastrointestinal tract. The immunohistochemistry has a leading role, assisting with the differential diagnosis.
原发性膀胱黏液腺癌是一种极其罕见的泌尿系统疾病，在所有膀胱肿瘤中所占比例不到2%，且常表现为转移性。
一名69岁男性患者在接受经尿道膀胱肿瘤切除并对整个胃肠道进行全面检查以排除其他原发部位后，被诊断为原发性膀胱黏液腺癌。免疫组化证实了肿瘤的性质。该患者接受了根治性膀胱前列腺切除术、整块双侧盆腔淋巴结清扫术以及Bricker回肠造口术进行尿流改道。
原发性腺癌造成了诊断难题，因为它难以与起源于结肠和前列腺的腺癌相区分。我们主张在排除任何与胃肠道相关的原发性恶性部位后，采取根治性手术治疗。免疫组化在辅助鉴别诊断方面起着主导作用。
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