Wen Han, Marsolo Keith A, Bennett Eric E, Kutten Kwame S, Lewis Ryan P, Lipps David B, Epstein Neal D, Plehn Jonathan F, Croisille Pierre
National Heart, Lung and Blood Institute, National Institutes of Health, Bldg 10, B1D416, 10 Center Dr, Bethesda, MD 20892, USA.
Radiology. 2008 Jan;246(1):229-40. doi: 10.1148/radiol.2461070053.
The purpose of this study was to prospectively assess the effects of two adaptive postprocessing techniques on the evaluation of myocardial function with displacement-encoded magnetic resonance (MR) imaging, including sensitivity for abnormal wall motion, with two-dimensional echocardiography as the reference standard. Sixteen patients (11 men, five women; age range, 26-74 years) and 12 volunteers (six men, six women; age range, 29-53 years) underwent breath-hold MR imaging. Institutional review board approval and informed consent were obtained. Adaptive phase-unwrapping and spatial filtering techniques were compared with conventional phase-unwrapping and spatial filtering techniques. Use of the adaptive techniques led to a reduced rate of failure with the phase-unwrapping technique from 18.9% to 0.6% (P < .001), resulted in lower variability of segmental strain measurements among healthy volunteers (P < .001 to P = .02), and increased the sensitivity of quantitative detection of abnormal segments in patients from 82.5% to 87.7% (P = .034). The adaptive techniques improved the semiautomated postprocessing of displacement-encoded cardiac images and increased the sensitivity of detection of abnormal wall motion in patients.
http://radiology.rsnajnls.org/cgi/content/full/246/1/229/DC1.
本研究旨在以前瞻性方式评估两种自适应后处理技术对采用位移编码磁共振(MR)成像评估心肌功能的影响,包括对异常室壁运动的敏感性,并以二维超声心动图作为参考标准。16例患者(11例男性,5例女性;年龄范围26 - 74岁)和12名志愿者(6例男性,6例女性;年龄范围29 - 53岁)接受了屏气MR成像检查。获得了机构审查委员会的批准并取得了知情同意。将自适应相位解缠和空间滤波技术与传统相位解缠和空间滤波技术进行了比较。使用自适应技术使相位解缠技术的失败率从18.9%降至0.6%(P <.001),降低了健康志愿者节段应变测量的变异性(P <.001至P =.02),并将患者异常节段定量检测的敏感性从82.5%提高到87.7%(P =.034)。自适应技术改善了位移编码心脏图像的半自动后处理,并提高了患者异常室壁运动检测的敏感性。
http://radiology.rsnajnls.org/cgi/content/full/246/1/229/DC1