Monti A, Cogiamanian F, Marceglia S, Ferrucci R, Mameli F, Mrakic-Sposta S, Vergari M, Zago S, Priori A
Neurostimulation Unit, Department of Neurological Sciences, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy.
J Neurol Neurosurg Psychiatry. 2008 Apr;79(4):451-3. doi: 10.1136/jnnp.2007.135277. Epub 2007 Dec 20.
Transcranial direct current stimulation (tDCS) has been proposed as an adjuvant technique to improve functional recovery after ischaemic stroke. This study evaluated the effect of tDCS over the left frontotemporal areas in eight chronic non-fluent post-stroke aphasic patients. The protocol consisted of the assessment of picture naming (accuracy and response time) before and immediately after anodal or cathodal tDCS (2 mA, 10 minutes) and sham stimulation. Whereas anodal tDCS and sham tDCS failed to induce any changes, cathodal tDCS significantly improved the accuracy of the picture naming task by a mean of 33.6% (SEM 13.8%).
经颅直流电刺激(tDCS)已被提议作为一种辅助技术,用于改善缺血性中风后的功能恢复。本研究评估了tDCS对8名慢性非流畅性中风后失语患者左侧额颞区的影响。实验方案包括在阳极或阴极tDCS(2毫安,10分钟)及假刺激前后,对图片命名(准确性和反应时间)进行评估。阳极tDCS和假tDCS均未引起任何变化,而阴极tDCS显著提高了图片命名任务的准确性,平均提高了33.6%(标准误13.8%)。