Kim Mi Suk, Jeanty Philippe, Turner Cheryl, Benoit Bernard
Inner Vision Women's Ultrasound, Nashville, TN 37203, USA.
J Ultrasound Med. 2008 Jan;27(1):119-24. doi: 10.7863/jum.2008.27.1.119.
The purpose of this presentation is to show 3-dimensional development of the ventricles of the brain in early pregnancy, from 6 to 13 weeks, and to provide a reference for early diagnosis of central nervous system anomalies such as hydrocephalus and holoprosencephaly.
From March 2007 to August 2007, 46 patients were included. All patients had routine first-trimester 2- and 3-dimensional sonographic examinations at the same time. All cases were examined with a Voluson 730 Expert or Voluson E8 ultrasound scanner (GE Healthcare, Milwaukee, WI) using a 4- to 8- or 6- to 12-MHz transvaginal probe. Volumes were reviewed and analyzed with GE 4DView release 6 software. After the inversion-rendering mode was selected, volumes were dissected by the MagicCut function to show the ventricles.
A total of 34 volumes from 7 to 12 complete gestational weeks were successfully dissected. Those before 7 and after 12 weeks could not be dissected properly. The crown-rump length ranged from 12.7 to 68 mm. Twelve representative images of the rendered volumes in chronologic order are shown. The brain volume dissections of 2 fetuses with ventriculomegaly and alobar holoprosencephaly are shown for comparison.
Early human brain ventricular structures could be evaluated in vivo with 3-dimensional sonography. This presentation shows the timeline of brain development and provides reference images to compare possible anomalies of development.
本报告的目的是展示孕早期6至13周时脑室内的三维发育情况，并为脑积水和全前脑等中枢神经系统异常的早期诊断提供参考。
纳入2007年3月至2007年8月期间的46例患者。所有患者均在同一时间进行了孕早期常规二维和三维超声检查。所有病例均使用Voluson 730 Expert或Voluson E8超声扫描仪（GE Healthcare，密尔沃基，威斯康星州），采用4至8MHz或6至12MHz经阴道探头进行检查。使用GE 4DView 6版软件对容积数据进行回顾和分析。选择反转渲染模式后，通过MagicCut功能对容积数据进行切割以显示脑室。
成功切割了7至12个完整孕周的34个容积数据。7周前和12周后的容积数据无法正确切割。头臀长度范围为12.7至68毫米。按时间顺序展示了12幅渲染容积数据的代表性图像。还展示了2例脑室扩大和无脑叶全前脑胎儿的脑容积切割图像以作比较。
可通过三维超声对早期人脑室结构进行体内评估。本报告展示了脑发育的时间线，并提供了参考图像以比较可能的发育异常情况。
