Hattatoglu-Sönmez E, Ozcakar L, Gökce-Kutsal Y, Karaagaoglu E, Demiralp B, Nazliel-Erverdi H
Department of Periodontology, Faculty of Dentistry, Hacettepe University, Ankara, Turkey.
J Dent Res. 2008 Jan;87(1):79-83. doi: 10.1177/154405910808700114.
Alveolar bone destruction can be magnified in the presence of generalized skeletal disorders. We questioned whether severe generalized periodontitis patients display signs of bone metabolism disturbances. Our objective was to assess skeletal bone mineral density (BMD) and biochemical bone parameters in premenopausal women with periodontitis. Forty-five patients and 40 control individuals were included in the study. We measured BMD by dual-energy x-ray absorptiometry. The results showed no difference in BMD values between the periodontitis and control groups (p > 0.05). A positive relationship between the clinical attachment level and Body Mass Index (BMI) scores was observed (p = 0.03). Increased serum creatinine levels were noted in the periodontitis group (p = 0.04). Analysis of the data suggests that there is no evidence for an association between skeletal BMD and severe periodontitis in premenopausal women. There may be a link between elevated creatinine levels and periodontitis. The persons with high BMI scores seemed to be at risk for periodontitis.
在存在全身性骨骼疾病的情况下，牙槽骨破坏会加剧。我们质疑重度全身性牙周炎患者是否表现出骨代谢紊乱的迹象。我们的目的是评估绝经前牙周炎女性的骨骼骨密度（BMD）和生化骨参数。45名患者和40名对照个体被纳入研究。我们通过双能X线吸收法测量骨密度。结果显示，牙周炎组和对照组的骨密度值无差异（p>0.05）。观察到临床附着水平与体重指数（BMI）评分之间呈正相关（p = 0.03）。牙周炎组血清肌酐水平升高（p = 0.04）。数据分析表明，没有证据表明绝经前女性的骨骼骨密度与重度牙周炎之间存在关联。肌酐水平升高与牙周炎之间可能存在联系。BMI评分高的人似乎有患牙周炎的风险。
