儿童脑膜瘤
Meningiomas in children.
作者信息
Greene Stephanie, Nair Nathan, Ojemann Jeffrey G, Ellenbogen Richard G, Avellino Anthony M
机构信息
Department of Neurological Surgery, University of Washington School of Medicine, Seattle Children's Hospital and Regional Medical Center, Seattle, WA, USA.
出版信息
Pediatr Neurosurg. 2008;44(1):9-13. doi: 10.1159/000110656. Epub 2007 Dec 14.
OBJECTIVE
Pediatric meningioma is a rare diagnosis. This retrospective review seeks to elucidate pertinent characteristics of pediatric patients presenting with meningioma.
METHODS
The Seattle Children's Hospital and Regional Medical Center brain tumor database was surveyed from 1940 through 2004. Twenty patients were identified.
RESULTS
The median age of the 20 patients was 13 years. Five patients had radiation-induced meningiomas. Five patients had neurofibromatosis type 2. Ten patients had spontaneously arising meningiomas, 2 of which were malignant.
CONCLUSION
Patients with spontaneously arising meningiomas were younger than those with identified risk factors. There was no recurrence in patients with radiation-induced meningiomas. The only death occurred in a patient with a malignant meningioma.
目的
小儿脑膜瘤是一种罕见的诊断。本回顾性研究旨在阐明患有脑膜瘤的小儿患者的相关特征。
方法
对西雅图儿童医院及地区医疗中心1940年至2004年的脑肿瘤数据库进行了调查。共识别出20例患者。
结果
20例患者的中位年龄为13岁。5例患者患有放射性诱导的脑膜瘤。5例患者患有2型神经纤维瘤病。10例患者患有自发产生的脑膜瘤，其中2例为恶性。
结论
自发产生脑膜瘤的患者比有明确危险因素的患者年龄更小。放射性诱导的脑膜瘤患者无复发情况。唯一的死亡发生在一名患有恶性脑膜瘤的患者身上。
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