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[增殖性脓皮病作为HIV感染的早期迹象]

[Pyoderma vegetans as an early sign of HIV infection].

作者信息

Potekaev N S, Iurin O G, Gorbacheva Z S, Potekaev S N, Pokrovskiĭ V V

出版信息

Ter Arkh. 1991;63(11):78-80.

PMID:1810071
Abstract

Skin and mucosal lesions are described in a 40-year-old man who suffered from HIV infection in the stage of secondary diseases. The diagnosis was supported by demonstration of antibodies to HIV in the immune blotting test. The clinical manifestations were reduced to steady fever, generalized lymphadenopathy, pyoderma vegetans and chancriform pyoderma, candidiasis of the oral cavity, and seborrheic dermatitis, HIV infection was diagnosed 4 years after the appearance of pyoderma which initially was amenable by external antibacterial agents and then became resistant to them. Eruptions of pyoderma vegetans simulating wide condylomas were located in inguinal folds, on the internal surface of the thighs and scrotum; the chancriform focus was located in the internal preputial layer. The treatment with azothymidine combined with antibacterial and antimycotic agents led to the improvement of the patient's general status and to the reduction of local lesions. However, on recommendations of an unknown witch doctor who started treating him with the aid of reflexotherapy, phytotherapy and bioenergetic actions the patient stopped receiving the treatment prescribed and did not report for control examinations. After 5 months he died of brain edema.

摘要

一名40岁男性,处于艾滋病继发疾病阶段,出现了皮肤和黏膜病变。免疫印迹试验中检测到抗HIV抗体,支持了该诊断。临床表现为持续发热、全身淋巴结肿大、增殖性脓皮病和下疳样脓皮病、口腔念珠菌病以及脂溢性皮炎。在出现最初可用外用抗菌剂治疗、后来产生耐药性的脓皮病4年后,该患者被诊断为HIV感染。类似广泛湿疣的增殖性脓皮病皮疹位于腹股沟皱襞、大腿内表面和阴囊;下疳样病灶位于包皮内层。齐多夫定联合抗菌和抗真菌药物治疗使患者的一般状况得到改善,局部病变减轻。然而,在一位不知名巫医的建议下,患者开始接受反射疗法、植物疗法和生物能量疗法,停止了规定的治疗,也未前来进行复查。5个月后,他死于脑水肿。

相似文献

1
[Pyoderma vegetans as an early sign of HIV infection].[增殖性脓皮病作为HIV感染的早期迹象]
Ter Arkh. 1991;63(11):78-80.
2
An unusual presentation of blastomycosislike pyoderma (pyoderma vegetans) and a review of the literature.芽生菌病样脓皮病(增殖性脓皮病)的一种不寻常表现及文献综述。
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[Erosive pustular dermatosis of the scalp. A new entity or a variant of pyoderma vegetans].[头皮糜烂性脓疱性皮病。一种新的疾病实体还是增殖性脓皮病的一种变异型]
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PYODERMA VEGETANS WITH lg A DEFICIENCY.伴有IgA缺乏的增殖性脓皮病
Indian J Dermatol. 2010 Oct;55(4):379-80. doi: 10.4103/0019-5154.74556.