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[孕期主动脉瓣和二尖瓣两个瓣膜假体复发性血栓形成的尿激酶和链激酶溶栓治疗]

[Fibrinolytic treatment with urokinase and streptokinase for recurrent thrombosis in two valve prostheses for the aortic and mitral valves during pregnancy].

作者信息

Tissot H, Vergnes C, Rougier P, Bricaud H, Dallay D

机构信息

Maternité C, Hôpital Pellegrin, Bordeaux.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1991;20(8):1093-6.

PMID:1811007
Abstract

The authors report a case of a patient who had two episodes of valvular thrombosis successfully treated with fibrinolysis using urokinase and streptokinase. They emphasise how efficient these treatments are in spite of the gravity of the initial picture and also point out the dangers and difficulties that can occur because of the risk of haemorrhage in pregnancy, and particularly during delivery and post-partum. They show once more that the treatment is harmless for the fetus. They conclude that using fibrinolytic treatment should be considered first when there is great danger to the patient, and the advantages and disadvantages of thrombolysis should be weighed up.

摘要

作者报告了一例患者,该患者发生了两次瓣膜血栓形成,使用尿激酶和链激酶进行纤维蛋白溶解治疗后成功治愈。他们强调,尽管初始病情严重,但这些治疗方法非常有效,同时还指出了由于妊娠期间,尤其是分娩和产后出血风险可能出现的危险和困难。他们再次表明该治疗方法对胎儿无害。他们得出结论,当患者面临巨大危险时,应首先考虑使用纤维蛋白溶解治疗,并权衡溶栓的利弊。

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